Hispanic men with advanced prostate cancer have improved overall survival compared with their non-Hispanic White (NHW) counterparts, a finding consistent with what previously has been described as the “Hispanic paradox,” investigators reported in a poster presentation at the 22ndannual meeting of the Society of Urologic Oncology.

Among patients with private insurance/managed care coverage at diagnosis, Hispanic men had a significant 27% decreased risk for death compared with NHW men in adjusted analyses, according to Zachariah Taylor, DO, of Main Line Health in Bryn Mawr, Pennsylvania, and colleagues. Among men with Medicare coverage, Hispanic men had a significant 37% decreased risk for death compared with both NHW men and Black men.

“Despite socioeconomic and demographic similarities to Black men with advanced prostate cancer as well as higher rates of stage IV disease, Hispanic men demonstrate improved overall survival compared to non-Hispanic White men,” Dr Taylor’s team concluded. 


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The study was a retrospective review of the National Cancer Database from 2004 to 2017 and included 67,238 men who underwent radical prostatectomy or radiation therapy for stage 3 or 4 prostate cancer.

The investigators found no significant interaction between insurance status and race or ethnicity with respect to improved overall survival.

Reference

Taylor Z, McGreen B, Buckley M, Cahn D. Hispanic paradox and insurance status associations in advanced prostate cancer: A National Cancer Database study. Presented at the 22nd annual meeting of the Society of Urologic Oncology, December 1-3, 2021. Poster 101.