The Changing Treatment Paradigm for IgAN
Clinicians have a growing number of options for treating immunoglobulin A nephropathy.
NKF 2023 Spring Clinical Meetings
Zetomipzomib Reduces Proteinuria in Proliferative Lupus Nephritis
Kidney function remained stable throughout the 25 week treatment period.
Conservative Kidney Management Often a Better Option for Older Adults With ESKD
In many cases, older patients with end-stage kidney disease would be better off with conservative kidney management focused on enhancing quality of life rather than going on dialysis.
Kidney Function Stable During 12 Months of Pegloticase-Methotrexate for Gout
Kidney function was not harmed over 52 weeks of pegloticase and methotrexate co-therapy in patients with uncontrolled gout at baseline.
Proteinuria Reduction in IgA Nephropathy Greater With Sparsentan
Sparsentan is a dual endothelin and angiotensin receptor antagonist.
CKD Increases Odds of AKI Requiring Dialysis in Inpatients With Pneumonia
The rate of AKI requiring dialysis among patients hospitalized with pneumonia was 2.5% for those with CKD compared with 0.03% for those without CKD.
Hyperkalemia Recurrence Common in CKD Despite Medical Nutrition Therapy
Medical nutritional therapy may need to be combined with anti-hyperkalemia therapy to prevent recurrence, investigators suggested.
SGLT2 Inhibitor Plus MRA Further Reduces Albuminuria
Study findings indicate synergistic effects of SGLT2 inhibitors and MRAs on albuminuria.
RBC Transfusions Commonly Lead to Hyperkalemia, Hospitalization in CKD
Use of intravenous iron and ESAs was low among patients with stage 3 to 5 CKD.
Upper GI Erosions Are the Most Frequent Non-CV Events in the Dialysis Population
The rate of esophageal and gastric erosions among patients on dialysis eligible for anemia treatment was approximately 49 events per 100 patient-years, investigators report.
Red Blood Cell Transfusion Rate Highest With Persistent ESA Hyporesponse
Patients receiving peritoneal dialysis rather than hemodialysis or both modalities have the lowest rate of ESA hyporesponse.
Holistic Care Lacking for Patients Who Forgo Kidney Replacement Therapy
Survey findings highlight the need to train staff on comprehensive conservative care.
ESA Hyporesponse Tied to Adverse Events in Dialysis Population
Patients with persistent ESA hyporesponse had especially high rates of adverse events.
Diabetic Kidney Disease in US Veterans Characterized
The prevalence of diabetic kidney disease is higher among US veterans than the general population, investigators noted.
Hypertension Risk Higher for Black Living Kidney Donors
Black living kidney donors have a significant 17% higher risk for systolic hypertension compared with their White counterparts.
New Questionnaire Captures Symptoms, Burden of CKD Anemia
The new tool goes beyond hemoglobin measurement to include the effects of anemia on patients’ quality of life.
Healthy Diets Fail to Improve Survival Outcomes in the ESKD Population
Investigators report no significant improvement in cardiovascular or overall mortality in patients on dialysis.
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