Lupus nephritis recurrences, while rare, typically happen within a few years of kidney transplantation.
Tenapanor inhibits the sodium hydrogen exchanger 3 (NHE3), reducing paracellular uptake of phosphate in the intestine.
Add-on voclosporin improved complete renal response across all lupus nephritis biopsy classes, with the greatest benefit observed in pure class 3.
Interventions may be needed to achieve gender and racial equity in access to kidney transplantation across end-stage renal disease networks in the United States.
Investigators report encouraging results from a small observational study testing the effect of preemptive therapeutic plasma exchange and rituximab in kidney transplant recipients whose primary cause of kidney failure was focal segmental glomerulosclerosis.
In a study of Black patients with COVID-19, those with 2 APOL1 risk alleles have increased odds of acute kidney injury.
Oral sodium bicarbonate therapy given to patients with chronic kidney disease increases urinary pH but also increases urinary citrate levels, which may mitigate the risk for calcium phosphate stone formation.
Nearly two-thirds of inpatients with a hyperkalemia diagnosis do not receive potassium binders, according to a contemporary analysis.
Autosomal dominant polycystic kidney disease progresses to kidney failure faster in Hispanic patients than in those of other races or ethnicities, a study found.
An analysis of contemporary ESA utilization among patients with anemia of nondialysis-dependent chronic kidney disease may help identify optimal candidates for treatment.
Each 1 mEq/L increase in serum bicarbonate in kidney transplant recipients is associated with a 10% reduction in graft failure risk, a study found.
The downstream effects of medical care reduction on health outcomes, such as hospitalizations or dialysis preparedness, requires further study, according to the investigators.
Nearly 74% of hemodialysis patients experienced pre-dialysis hyperkalemia within 1 year of enrollment in the Dialysis Outcomes and Practice Patterns Study, according to investigators.
Roxadustat reduced the need for rescue therapy among patients with any stage of chronic kidney disease.
Nephrologists rarely explained the clinical meaning of rapid progression, according to patients.