|The following article features coverage from the National Kidney Foundation’s 2019 Spring Clinical Meetings. Click here to read more of Renal & Urology News’ conference coverage.|
Clinical presentations of catheter-related bloodstream infections (CRBSIs) in patients on hemodialysis (HD) varies according to the causative pathogen, study findings presented at the National Kidney Foundation’s 2019 Spring Clinical Meetings in Boston suggest.
For example, patients with Staphylococcus aureus and Gram negative CRBSIs are the most likely to present with fever, rigor or both, Crystal A. Farrington, DO, and Michael Allon, MD, of the University of Alabama at Birmingham reported in a poster presentation. Staphylococcus epidermidis CRBSIs tend to present with nonspecific symptoms.
The study, which was a retrospective analysis of CRBSIs in 249 HD patients, found S. aureus and Staphlococcus epidermidis caused 34% and 38% of CRBSIs, respectively. Gram negative bacteria accounted for 20% of CRBSIs. Polymicrobial infections accounted for 14% of CRBSIs and are associated with longer duration of catheter use, according to the investigators.
Hospitalization occurred more frequently with S. aureus CRBSIs, but the median length of hospital stay was similar for all organisms and relatively short, “suggesting that CRBSI tends to improve quickly once appropriate antibiotics are initiated,” Drs Farrington and Allon wrote.
The median length of stay was 4 days for S. aureus and S. epidermidis CRBSIs and 5.5 days for Gram negative CRBSIs.
Read more of Renal & Urology News’ coverage of NKF’s 2019 Spring Clinical Meetings by visiting the conference page.
Farrington CA, Allon M. The impact of infecting organism on the clinical presentation and complications of hemodialysis catheter-related bloodstream infections. Presented at the National Kidney Foundation’s 2019 Spring Clinical Meetings held May 8-12 in Boston. Poster 304.