LAS VEGAS—Pulmonary hypertension is a strong predictor of the need for renal replacement therapy (RRT) after lung transplantation, according to researchers. Moreover, RRT is associated with significant in-hospital mortality.
Alaine Gada, MD, and colleagues at Cleveland Clinic in Ohio reviewed data from 657 lung transplant recipients. Of these, 40 (6%) required RRT. After adjusting for multiple variables, pulmonary hypertension was independently associated with a 6.4 times increased risk for needing RRT, the investigators reported at the National Kidney Foundation’s Spring Clinical Meetings. Thirty-four patients died during the post-operative period, 13 (32%) in the RRT group and 21 (3%) in the group not requiring RRT.
In addition, after adjusting for race, age, type of lung transplant, pulmonary hypertension, pre-transplant diabetes, and baseline estimated glomerular filtration rate, the need for post-transplant RRT independently predicted a 2.8 times increased risk for in-hospital death.
Enjoying our content?
Thanks for visiting Renal & Urology News. We hope you’re enjoying the latest clinical news, full-length features, case studies, and more.
You’ve viewed {{metering-count}} of {{metering-total}} articles this month. If you wish to read unlimited content, please log in or register below. Registration is free.
{{login-button}} {{register-button}}
Log in to continue reading this article.
Don’t miss out on today’s top content on Renal & Urology News. Register for free and gain unlimited access to:
- Clinical News, with personalized daily picks for you
- Case Studies
- Conference Coverage
- Full-Length Features
- Drug Monographs
- And More
{{login-button}} {{register-button}}
Want to read more?
Please login or register first to view this content.