Investigators report findings from the MIRROR RCT trial, which compared pegloticase plus methotrexate vs placebo for uncontrolled gout.
New findings suggest active surveillance should be performed in this population and should not preclude transplant eligibility, according to investigators.
Treatment with an SGLT2 inhibitor may help patients with CKD or type 2 diabetes better preserve their kidney function.
In a study, acute kidney injury and acute kidney disease developed in 51.4% and 37.5% of patients who underwent radical cystectomy for muscle-invasive bladder cancer.
Study underscores the importance of maintaining or increasing lean body mass during weight loss.
Investigators compared the therapies in a large national cohort of patients with normal kidney function.
Data from real-world practice and a meta-analysis of randomized controlled trials concur.
A greater proportion of younger adults are at risk under the age-adapted CKD classification system.
Study of US veterans with normal kidney function at baseline found that bicarbonate users had a significant 2.0- and 3.3-fold increased risk for incident CKD and death, respectively.
Since FDA approval of imtainib, 40 newer tyrosine kinase inhibitor agents have been approved.
New findings have important implications in the new era where delaying dialysis initiation is a priority goal by means of continued conservative management of hyperkalemia, according to investigators.
In the final 12 months of a 7-year study period (January 2015 to April 2022), endocrinologists accounted for 11-fold more SGLT2 inhibitor prescriptions than nephrologists, investigators report.
Given the widespread use of contrast medium in cardiovascular and other imaging, continued focus on preventing contrast-induced acute kidney injury is warranted.
Demand for living kidney donors has only grown, spurring investigators to study the risks and health consequences of donation, such as acute kidney injury.
Patients with hyponatremia and other risk factors for dementia might need closer monitoring.
Danish investigators compared direct oral anticoagulants with vitamin K antagonists in 33,670 patients with atrial fibrillation.
Recent study included 980 individuals older than 65 years who participated in the Cardiovascular Health Study.
Underweight also has been linked to cardiovascular disease and early mortality in a general population.
Currently, there is no standard regimen for maintenance iron supplementation in patients receiving hemodialysis.
If renin-angiotensin system inhibitors are indicated in patients with advanced CKD, they should not be stopped just because of low eGFR, investigators concluded.