SAN DIEGO—Pre-dialysis transplant recipients with a high level of kidney function do not appear to benefit from their transplant more than pre-dialysis recipients with a low level of kidney function, data show.

The findings, presented here at the American Society of Nephrology’s Renal Week conference, suggest that pre-dialysis patients need not rush to have a preemptive transplant.

Patients who have undergone preemptive transplantation tend to live longer and have higher functioning transplants than post-dialysis transplant recipients. However, studies have not looked whether higher kidney function among pre-dialysis recipients improves patients’ long-term health.

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Using data from the United Network for Organ Sharing, researchers at Stanford University School of Medicine in Stanford, Calif., identified 25,748 preemptive transplant recipients and divided them into two groups: patients with higher kidney function and patients with lower kidney function at the time of transplant.

Patient and kidney transplant survival were similar in the two groups. The high-level group had a 34% decreased risk of acute rejection at six months post-transplant and a 35% reduced risk of requiring dialysis within the first week after transplantation.

“Based on these findings, we feel that patients and transplant experts anticipating a preemptive kidney transplant can wait for clinical indications to emerge without any significant loss of survival advantage associated with a preemptive transplant,” said Basit Javaid, MD, Assistant Professor of Medicine at Stanford.