Tenapanor May Improve Uncontrolled Hyperphosphatemia
By blocking paracellular phosphate transport, tenapanor added to phosphate binders may improve the hyperphosphatemia management in patients on maintenance dialysis, a study found.
Kidney Week 2019
In-Depth Focus From Kidney Week 2019: Hemodialysis-Dependent Chronic Kidney Disease
Complete Coverage
Adding Aliskiren to Losartan Ups Hyperkalemia Risk in CKD
Adding aliskiren to losartan in patients with nondiabetic chronic kidney disease does not result in a greater renal protection and increases their risk of hyperkalemia, a study found.
Stopping ACE Inhibitors, ARBs After Hyperkalemia Episode Ups Death Risk in CKD
Patients with CKD who discontinued ACE inhibitors or angiotensin receptor blockers after a hyperkalemia episode had a 2.6-fold increased risk of all-cause mortality compared with patients who continued taking the drugs.
Roxadustat Superior to Epoetin Alfa in New Dialysis Patients
Newly released safety data also show that roxadustat is associated with reduced cardiovascular risks compared with epoetin alfa.
Metabolic Acidosis in CKD Underdiagnosed, Undertreated
In a study, approximately one-fifth of CKD patients with metabolic acidosis received a diagnostic code for it.
Hyperkalemia Ups CKD Progression Risk
Hyperkalemia in patients with chronic kidney disease (CKD) stage 3 or 4 more than doubles their risk of progressing to CKD stage 5, a study found.
Gout Ups Risks of Kidney Transplant Complications, Return to HD
Gout that develops in kidney transplant recipients increases their risk of worse outcomes, according to 2 new studies.
Frail Hemodialysis Patients Tend to Worsen Over Time
In a study, two-thirds of hemodialysis patients met criteria for frailty, which impairs independence, cognition, mood, and quality of life.
Magnesium-Containing Antacids May Increase Fracture Risk
Kidney disease patients who took magnesium-containing antacids were 15% more likely to experience hip fracture than nonusers of antacids.
Overhydration Is a Risk Factor for Post-Dialysis Hypertension
In turn, individuals with post-dialysis hypertension have significantly greater risks for all-cause mortality.
ESA Hyporesponsiveness Linked to Abnormal FGF23 Levels
In a study, hemodialysis patients with the highest and lowest FGF23 levels had higher risks for ESA hyporesponsiveness.
Novel Drug Eases Uremic Pruritus
In a phase 3 trial, difelikefalin, a kappa opioid receptor agonist, significant decreased itching and improved itching-related quality of life among dialysis patients suffering from pruritus.
Preoperative ARB Use May Increase AKI Risk After Surgery
Adult patients who used angiotensin receptor blockers prior to surgery had significant 30% increased odds of acute kidney injury, an Icelandic study found.
Spironolactone Does Not Prevent Diabetic Nephropathy in Type 2 Diabetes
In a study, spironolactone treatment was not significantly better than placebo in preventing diabetic nephropathy in patients with high-risk type 2 diabetes.
Potassium Binder Found Effective Regardless of Hyperkalemia Severity
In a pooled analysis of data from 3 studies, patiromer lowered potassium levels into a target range of 3.8 to 5.0 mEq/L in 92.5% and 96.8% of patients with baseline potassium levels of 6.0 mEq/L or higher and less than 6.0 mEq/L, respectively.
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