PHILADELPHIA—Plant sources of dietary phosphorus should be encouraged to avoid high phosphorus burden in patients with chronic kidney disease (CKD), according to a new study presented at Kidney Week 2014.
Researchers led by Anuja Shah, MD, of Harbor-UCLA Department of Nephrology, and fellow researchers measured urine phosphorus in 5 different stage 4 or 5 CKD patients who were living in a metabolic balance ward. Their goal was to measure the effects of 5 different dietary sources of phosphorus (plant, inorganic, meat, dairy, mixed) to study their effects on intestinal phosphorus absorption as well as 24-hour urinary phosphorus excretion.
Patients were examined on five separate occasions in two-week intervals each, and diets included 800 mg of calcium as well as 1,000 mg of phosphorus per day.
They found that the plant-based diet demonstrated the lowest urinary phosphorus excretion while the inorganic-based diet had the highest.
“Inorganic phosphorus is the most readily intestinal absorbed source of dietary phosphorus,” the authors noted. “This is the first study to examine the effects of five different food sources of phosphorus on intestinal phosphorus absorption in CKD patients.”