Study: IV Iron Use Less with Once-Monthly ESA
Once-monthly injections of peginesatide are as effective as one to three injections per week of epoetin in maintaining hemoglobin levels.
Kidney Week 2012 Anemia
Hematocrit Decreases as eGFR Declines
Hematocrit decreases as estimated glomerular filtration rate (eGFR) declines in hypertensive chronic kidney disease (CKD) patients.
Daily Hemodialysis Linked to Worsening Hb Levels
Patients initiating daily hemodialysis (DHD) face a significant decrease in mean hemoglobin (Hb), hematocrit, and transferrin.
IV Ascorbic Acid May Benefit EPO Resistant Patients
Intravenous ascorbic acid (IVAA) can be a potent and effective adjuvant treatment for hemodialysis patients who have normoferritinemic anemia resistant to treatment with erythropoietin (EPO).
Races Show Similar Declines in Epoetin Use, Hb Levels
Epoetin use and hemoglobin (Hb) levels have declined similarly for black and non-black dialysis patients following the advent of Medicare’s system of “bundled” payments.
Low Iron, Intradialytic Hypotension Linked
Iron deficiency in the absence of anemia is associated with intradialytic hypotension (IDH), a finding that suggests iron has a role beyond erythropoiesis.
EPO Use Down, IV Iron Use Up
Clinicians are prescribing less erythropoietin and more intravenous iron for anemic hemodialysis patients after the introduction of a prospective payment system (PPS) for dialysis services (“bundling”) and changes to ESA drug labels.
Sickle Cell Trait Associated with More ESA Use
Variant hemoglobin (Hb) is common in African-American hemodialysis patients and it is associated with a need for significantly increased doses of ESA.
IV Iron Dosing Has Modest Effects at Higher TSAT
Dosing intravenous (IV) iron at higher TSAT levels has only a modest effect on raising transferrin saturation (TSAT), ferritin, and hemoglobin in anemic hemodialysis patients.
Bolus Iron Dosing Hikes Risk of Serious Infection
Bolus dosing of intravenous (IV) iron is associated with an elevated risk of infection-related hospitalization among anemic hemodialysis (HD) patients compared with maintenance dosing.
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