Kidney Week 2021

Conference Coverage

Steroid Reduces the Risk for Major Adverse Kidney Events in IgA Nephropathy

By

Natasha Persaud

A reduced-dose steroid regimen in high-risk IgaN may offer the best balance of risks vs benefits, an investigator stated.

Chlorthalidone Safe, Effective for Treating Hypertension in Advanced CKD

By

Jody A. Charnow

In a study of patients with stage 4 chronic kidney disease and poorly controlled blood pressure, chlorthalidone significantly decreased systolic blood pressure compared with placebo.

Earlier Dialysis Transition May Decrease Survival

By

Natasha Persaud

In 2020, nearly 72% of patients in a US study initiated dialysis at an eGFR of 10 mL/min/1.73 m2 or higher.

Predictors of AKI Related to Immune Checkpoint Inhibitor Use Identified

By

Jody A. Charnow

Lower baseline kidney function and proton pump inhibitor use increased the risk for acute kidney injury associated with immune checkpoint inhibitor therapy.

Metabolic Acidosis in CKD Linked to Higher Kidney Stone Risk

By

Jody A. Charnow

Metabolic acidosis was defined as serum bicarbonate values of 12 or higher but less than 22 mEq/L.

Blood Transfusions in Kidney Transplant Recipients Raise VTE Risk

By

Jody A. Charnow

Receipt of any RBC transfusion was significantly associated with increased risk for venous thromboembolism.

Multiple Comorbidities in CKD Up Risks for Major Cardiovascular Events

By

Natasha Persaud

Multimorbidity is more common in patients with chronic kidney disease (CKD) than any other long-term condition, according to investigators.

SGLT2 Inhibitors Appear Protective in CKD, Kidney Transplantation

By

Natasha Persaud

SGLT2 inhibitors are associated with an initial dip in eGFR, so nephrologists need to monitor kidney function.

SHPT Treatment Tied With Lower Dementia Risk

By

Natasha Persaud

Elevated parathyroid hormone has been reported as a potential risk factor for cognitive impairment.

COVID-19 Survivors Face Greater Burden of AKI, CKD

By

Jody A. Charnow

Patients who survive the first 30 days of COVID-19 are more likely to have acute kidney injury and chronic kidney disease compared with those who do not contract the disease.

CKD Progression Linked to Higher Oxalate Levels

By

Jody A. Charnow

Data suggest that higher oxalate levels increase the risk for incident CKD.

Low Selenium Levels Linked With Poor Response to ESAs in Hemodialysis

By

Natasha Persaud

Previous studies indicate that selenium and selenoproteins are involved in erythropoiesis.

Daprodustat Has Efficacy Similar to ESAs for Renal Anemia

By

Jody A. Charnow

Daprodustat is as effective as erythropoiesis-stimulating agents in treating anemia in patients with dialysis-dependent and nondialysis-dependent chronic kidney disease.

Obesity in Glomerulonephritis May Increase Risk for ESKD

By

Natasha Persaud

Obesity rates in glomerular disease have multiplied more than 10-fold over the last 40 years.

Hepatitis C Treatment May Decrease the Risk for End-Stage Kidney Disease

By

Natasha Persaud

Nephrologists are in a prime position to identify HCV-infected patients and refer them for treatment with DAAs, according to investigators.

Hypertension in Offspring Tied to Maternal Hypertension, Hypertensive Disorders of Pregnancy

By

Jody A. Charnow

Offspring exposed to hypertensive disorders of pregnancy in gestation and those with maternal hypertension should be considered an elevated risk group, investigators concluded.

Metabolic Acidosis Ups Risk for Infection-Related Hospitalization

By

Jody A. Charnow

Serum bicarbonate levels less than 20 mEq/L are associated with increased risk for infection-related hospitalization.

Medical Management May Be Sufficient for Hyperkalemia

By

Natasha Persaud

Nationally standardized treatment algorithms for hyperkalemia should be developed, according to investigators.

Biomarkers Predict Major Adverse Kidney Events in COVID-19 Cases

By

Jody A. Charnow

Plasma levels of tumor necrosis factor receptors 1 and 2 are robust predictors of major adverse kidney events.

Long-Term Aspirin Use May Lower CKD Progression Risk

By

Jody A. Charnow

Long-term aspirin use by patients with nondialysis chronic kidney disease is associated with a lower risk for adverse kidney outcomes and death, a study found.