ATLANTA—Moderate or severe periodontal disease (MSPD) is associated with an increased risk of death among patients with chronic kidney disease (CKD), researchers reported at the American Society of Nephrology’s Kidney Week 2013 meeting.

Compared with individuals who had neither CKD nor MSPD, those with MSPD but no CKD had a significant 42% increased risk of death. Subjects with CKD but no MSPD had a 63% increased risk. Individuals with both CKD and MSPD had a nearly 2.3 times increased risk.

These results are from a study of 10,755 participants in the Third National Health and Nutrition Examination Survey (NHANES III) conducted by Ambarish Athavale, MD, of the University of Illinois in Chicago and collaborators. They defined MSPD as a loss of attachment of 6 mm or greater in at least two mesial sites and greater than 5 mm pocket depth in at least one mesial site (severe PD) or loss of attachment of 4 mm or greater in at least two mesial sites or at least two mesial sites with 5 mm pocket depth not on the same tooth (moderate PD).

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MSPD was more common in subjects with CKD than in those without CKD (9.2% vs. 4.8%). A total of 1,773 deaths occurred during a follow-up of 14 years.