SAN FRANCISCO—More than a quarter of women in the United States experience significant nocturia, Michael Daugherty, MD, of SUNY Upstate Medical University in Syracuse, reported at the American Urological Association’s 2018 annual meeting.

“Nocturia can be one of the most bothersome lower urinary tract symptoms, and it significantly affects quality of life. In both men and women, nocturia has been associated with depression and falls,” Dr Daugherty told Renal & Urology News. “Given its alarming prevalence and severity, physicians treating women should remember to ask about nocturia. Treating nocturia may help prevent complications, and it may uncover additional systemic medical concerns.”

Of 7620 women from the NHANES database 2009–2014, Dr Daugherty and colleagues found that 28.8% reported 2 or more urination episodes per night. The incidence of moderate nocturia steadily increased with age, from 16.4% of women aged 20 to 29, 33% of women aged 50 to 59, and 46.6% of women aged 80 and older. Women generally reported higher rates of nocturia than men of the same age.

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The team investigated the potential influence of gynecologic and obstetric history on nocturia. Among childbearing women, delivery type, parity, urinary prolapse, and previous hysterectomy had no associations with nocturia. Multivariable analysis, however, revealed that older age, black race, body mass index of 30 kg/m2 or higher, urge incontinence, poor overall health, arthritis, hypertension, or major depression had higher nocturia rates than those without these factors. Notably, women with higher levels of education and household income enjoyed lower rates of nocturia.

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Daugherty M, Ginzburg N, and Byler T. Prevalence of nocturia in US women: results from NHANES. Presented at the American Urological Association’s 2018 annual meeting in San Francisco, May 18–21. PD32-03.