Women in service-related occupations were 40% more likely to complain of nocturia than office workers with easy access to bathrooms.
Men with metabolic syndrome or a smoking history had more than triple the risks for persistent moderate to severe nocturia after TURP.
Nocturnal polyuria risk factors such as sleep apnea and pedal edema were underrepresented in the sample population compared with the general population.
Two phase 3 placebo-controlled randomized trials show the formulation significantly prolongs the first uninterrupted sleep period and proportion of nights with 1 or fewer nocturic episodes.
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