PHILADELPHIA—Nocturnal polyuria is nearly one third of women with overactive bladder (OAB), according to study findings presented at the International Continence Society’s 2018 annual meeting.

Nocturia is the only useful predictor of nocturnal polyuria, investigators concluded.

In a study of 1071 women with OAB, Sheng-Mou Hsaio, MD, of Far Eastern Memorial Hospital in New Taipei, Taiwan, and colleagues also found that 319 of them (30%) had nocturnal polyuria. The prevalence of the condition was greater among women aged less than 65 years than those aged 65 years and older (35.9% vs 17.4%), the investigators reported.

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In multivariate analysis, age, parity, OAB-wet, daytime frequency, and nocturia was associated with the odds of nocturnal polyuria.

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Nocturia was associated with significant 52% increased odds of nocturnal polyuria, whereas OAB-wet, parity, and daytime frequency were associated with significant 39%, 17%, and 8% decreased odds, respectively.

Receiver operating curve analyses showed that 5 or more nocturia episodes recorded in a 3-day bladder diary was an optimal cut-off value for predicting nocturnal polyuria, with a sensitivity and specificity of 85.6% and 61%, respectively.

According to the investigators, nocturnal polyuria was present if the proportion of 24-hour nighttime voided urine volume exceeded 33% among women aged 65 years or older and exceeded 20% among women younger than 65.


Hsiao S, Chang T, Chen C, et al. Prevalence and risk factors of nocturnal polyuria in female overactive bladder syndrome. Data presented at the International Continence Society’s 2018 annual meeting in Philadelphia, August 28–31. Abstract 13