Metabolic syndrome in kidney stone formers is associated with short times to stone recurrence, British investigators reported at the 34th Annual European Association Congress in Barcelona, Spain.

In a study of 742 kidney stone formers, the risk of stone recurrence increased along with the number of MetS components. Compared with patients who had no MetS components, those with 1, 2, 3, and components had a significant 1.5-, 2.9-, 3.4-, and 8.1-fold increased risk of a first stone recurrence, according to Robert Geraghty, BMBS, BMedSci, and colleagues at the University Hospital Southampton NHS Foundation Trust in the UK.

The 15-year recurrence rate was 26% among patients without MetS components compared with 31%, 30%, 43%, and 40% for those with 1, 2, 3, and 4 MetS components.

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The study population had a mean age of 68 years and had a mean of 7.2 follow-up visits over a mean 18 years.

As defined by the National Cholesterol Education Program’s Adult Treatment Panel III, MetS components include hypertension, elevated fasting glucose, abdominal obesity, low serum high-density lipoprotein, and elevated triglycerides.


Geraghty R, Cook P, Somani B. Association between metabolic syndrome (MetS) and kidney stone disease recurrence: Outcomes from a retrospective cohort study with a mean follow-up of 18 years. Presented at the 34th Annual European Association of Urology Congress in Barcelona, Spain, March 15-19. Abstract 204