In a phase 2 trial, more than half of patients who received neoadjuvant chemotherapy for high-risk upper tract urothelial carcinoma had a pathologic response that was associated with improved survival.
In a small study of patients who underwent radical surgery for upper tract urothelial carcinoma, investigators found no evidence of tract seeding.
In a study, patients diagnosed with a psychiatric illness following their diagnosis of muscle-invasive bladder cancer had a nearly 2-fold increased risk of dying from their cancer.
A single-dose instillation of mitomycin C immediately following therapeutic ureteroscopy upper tract urothelial carcinoma decreased the risk of urothelial recurrence.
Neoadjuvant chemotherapy prior to radical surgery for high-grade upper tract urothelial carcinoma lowered the risk of disease recurrence in the bladder by 66%, a study found.
Urine cytology after an initial TURBT predicted risk for a second TURBT one month later.
Instillation of an investigational mitomycin gel formulation obviated the need for nephrectomy in nearly half of individuals with low-grade upper tract urothelial carcinoma.
New studies find no increase in biochemical recurrence risk following radical prostatectomy or radiation therapy associated with testosterone replacement therapy.
Users of atenolol had 59% and 55% decreased odds of intermediate- and high-risk prostate cancer being found on biopsy compared with nonusers.
Providers should biopsy patients who are on active surveillance for prostate cancer on a regular schedule, according to investigators.
Platelet levels above 250,000/μL prior to surgery for high-risk renal cell carcinoma are independently associated with a 1.5-fold increase risk for recurrence.
Positive surgical margins in patients undergoing partial nephrectomy for cT1b renal cell carcinoma are associated with worse 5-year recurrence-free and overall survival.
Elevated C-reactive protein levels prior to nephrectomy for renal cell carcinoma is associated with an increased risk of renal impairment, a study found.
In a large study of men with grade group 2 or 3 prostate cancer, cancer-specific mortality at 8 years was high at 6% and 11% for active surveillance and watchful waiting patients, respectively.
Preliminary results from TRoMbone pave the way for a full randomized controlled trial.
A study of American men showed that those who adhered to a low-fat diet were twice as likely as men consuming usual diets to have hypogonadism.
In a study, left-sided renal cell carcinoma (RCC) was associated with a 16% to 19% increased risk of dying from the malignancy compared with right-sided RCC.
A study at Memorial Sloan Kettering Cancer Center found that the 5-year probability of dying from bladder cancer following radical cystectomy dropped from 35% to 25%.
By 3 and 6 months, flow rate, post void residual, IPSS, quality of life, and prostate volume improved in patients treated with the Rezum system, which uses convective heating to ablate prostate tissue.
Androgen deprivation therapy for prostate cancer is associated with a 22% increased of any dementia and 29% increased risk of Alzheimer’s disease.
From 2014 to 2015, the incidence of prostate cancer distant metastases at diagnosis rose from 532.3 to 586.1 per million men aged 75 years or older, a study found.
Men with metabolic syndrome had 3-fold increased odds of prostate cancer detection on a repeat prostate biopsy.
Urinary stasis and other factors appear to play a role in its pathogenesis.
Among men with nonmetastatic castration-resistant prostate cancer, the risk of developing metastasis increased with decreasing PSA doubling time, a study found.
Among men with metastatic castration-resistant prostate cancer, bone pain is significantly associated with a 3-fold increased risk of skeletal-related events.
Among men who experience biochemical recurrence of prostate cancer after radical prostatectomy, a high confirmatory PSA predicts a greater likelihood of distant metastasis.
New study shows prolonged time to development of castration-resistant prostate cancer among men with absolute testosterone levels below 20 ng/dL.
In real-world practice, patients older than 65 taking abiraterone or enzalutamide were more likely to experience cardiac disorders, such as atrial fibrillation, than their younger counterparts.
In the contemporary era of more effective systemic therapies, complete surgical resection of RCC metastases is associated with improved survival, new findings suggest.
Users of hydrophilic, but not hydrophobic, statins, had a lower risk of being diagnosed with prostate cancer, a large retrospective study found.
In a study, radiation delivered to the primary prostate tumor in men with metastatic castration-resistant prostate cancer was associated with a 74% decreased risk of death from any cause.
Delaying surgery more than 10 weeks after diagnosis of pT3 renal cell carcinoma is associated with increased 5-year mortality risk.
Study of patients on active surveillance for renal cell carcinoma showed spontaneous tumor regression occurred more often among those with papillary or chromophobe than clear-cell histology.
From 2004 to 2014, the annual number of cases of ureteroscopy increased significantly from 9601 to 12,087.
Japanese investigators report that men with hyperinsulinemia, compared with those who did not have the condition, had a 3-fold higher risk of kidney stone formation.
The following article features coverage from the American Urological Association (AUA) 2019 meeting. Click here to read more of Renal & Urology News’ conference coverage. CHICAGO—Most kidney stone-related malpractice suits end in a verdict in favor of the physician or a hospital, even after appeal, investigators reported at the 2019 American Urological Association annual meeting.…
Annual stone incidence increased from 0.6% in 2005 to 0.9% in 2015.
New findings show substantial potential for reducing radiation exposure to patients by using ultrasound first in the diagnostic workup for suspected stones.
Almost half of men with Gleason 8 prostate cancer diagnosed on biopsy experience downgrading upon pathologic examination of radical prostatectomy specimens.
In a small study of radical cystectomy patients, perioperative hypogonadism persisted up to 90 days after surgery.
Men with larger vs smaller prostate gland sizes treated with Aquablation experienced similar improvement in International Prostate Symptom Score.
Chicago’s McCormick Place will host the 2019 American Urological Association annual meeting, which is expected to draw some 16,000 to 17,000 urologists and other practitioners.