Metabolic Syndrome Predicts Complications After Radical Nephrectomy

SAN DIEGO—Metabolic syndrome may independently predict an increased risk of complications following radical nephrectomy (RN), according to study findings presented at the American Urological Association annual meeting.

E. Will Kirby, MD, and colleagues at the University of North Carolina in Chapel Hill reviewed data from 3,337 patients who underwent RN, 7,446 who underwent radical prostatectomy (RP), and 1,082 who underwent radical cystectomy (RC). The data included perioperative information, 30-day postoperative complications, and mortality.

After controlling for gender, age, body mass index, and other potential confounders, metabolic syndrome was associated with a 1.6 times increased risk of complications following RN. The researchers found no significant association between metabolic syndrome and complications following RC and RP.