SAN DIEGO—Black men undergoing active surveillance (AS) for low-risk prostate cancer may need closer follow-up than non-black men, researchers reported at the American Urological Association annual meeting.
Compared with non-black men, black men on AS for initially diagnosed low-risk tumors are more likely to experience disease progression and to abandon AS, according to a study led by Ranko Miocinovic, MD, of Detroit Medical Center.
The study included 67 AAM and 72 non-AAM who had a median follow-up of 36 months and 48 months, respectively. During follow-up, 44 black men (65.6%) remained on AS and 23 (34.3%) underwent treatment—16 with radical prostatectomy (RP), six with radiation, and one with cryotherapy. In the non-black group, 59 (81.9%) remained on AS and 13 (18%) underwent treatment, six with RP and seven with radiation. No patient had a Gleason score higher than 8 or locally advanced on final post-RP pathology.
The three-year rate of freedom from overall treatment was 74%, with no significant difference between the groups. The three-year rate of freedom from disease progression was significantly lower for blacks than for non-blacks (76% vs. 93%).