Exposure of kidneys donated after circulatory death to prolonged cold ischemia time (CIT) is not associated with an increased burden of care, study findings presented at the 2019 American Transplant Congress suggest.
John Narvaez, MD, MPH, and Liise Kayer, MD, of the University at Buffalo in Buffalo, New York, studied 146 consecutive donation after circulatory death (DCD) kidney-only adult transplants. They stratified the recipients according to short (less than 30 hours) and long (30 hours or more) CIT.
The short and long CIT groups demonstrated no significant difference in hospital length of stay (8.4 vs 10.7 days), 30-day readmission (26.3% vs 23.6%), 6-month reoperation rate (14.8% vs 23.1%), urinary complications (5% vs 1.5%), and delayed graft function (53.1% 56.9%). The cumulative probability of graft failure was similar in both groups.
The long CIT donors were significantly more likely than the short CIT donors to be older than 40 years (70.3% vs 49.4%) and non-white (26% vs 7%).
Narvaez J, Kayler L. Impact of cold ischemia time on DCD kidney transplant outcomes. Presented at the 2019 American Transplant Congress in Boston, June 1-5. Abstract B158.