To start this activity, click Begin at the bottom of this pageFSGS: Talking Points for the Practicing Nephrologist

Release Date: July 2014

Expiration Date: July 2015


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Estimated time to complete the educational activity: 1 hour

This activity is jointly provided by Haymarket Medical Education and Renal & Urology News.

Statement of Need: Primary focal segmental glomerulosclerosis (FSGS) is a common glomerular disease in adults and ranks among the top causes of a primary glomerular disease causing end-stage renal disease (ESRD). Primary FSGS is, however, adiagnosis of exclusion that is reached after known causes of FSGS have been ruled out. The distinction between primary versus secondary FSGS is not always obvious, resulting in a number of patients with secondary FSGS undergoing unnecessary and potentially harmful immunosuppressive therapy.

Target Audience: This activity has been designed to meet the needs of nephrologists and
supporting clinicians who treat patients with FSGS.

Educational Objectives: After completing the activity, the participant should be betterable to:

  • Explain the differences between primary and secondary FSGS
  • Categorize patients according to whether they have nephrotic-range proteinuria or nephrotic
    syndrome
  • Formulate the most appropriate management strategy for individual patients with FSGS

Accreditation Statement: This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Haymarket Medical Education (HME) and Renal & Urology News. Haymarket Medical Education is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation: HME designates this enduring material for a maximum of 1.0 AMA PRA
Category 1 CreditTM
. Physicians should claim only the credit commensurate with the extent of
their participation in the activity.

Disclosure of Conflicts of Interest: In accordance with the ACCME Standards for Commercial Support, HME requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest. HME resolves all conflicts of interest in an effort to ensure independence, objectivity, balance, and scientific rigor in all its educational programs.

Furthermore, HME seeks to verify that all scientific research referred to, reported, or used in a CME/CE activity conforms to the generally accepted standards of experimental design, data collection, and analysis. HME is committed to providing its learners with highquality CME/CE activities that promote improvements in health care and not those of a commercial interest.

The faculty reported the following financial relationships with commercial interests whoseproducts or services may be mentioned in this CME activity:

Name of Faculty Reported Financial Relationship
Fernando C. Fervenza, MD, PhD Reports having received grants and research support from Genentech, QuestCor, Biogen Idec, and Sanofi. 

Richard J. Glassock, MD Reports no relevant financial relationships

Sanjeev Sethi, MD, PhD Reports no relevant financial relationships

HME staff involved in the planning of this activity has no relevant financial relationships to disclose.

Renal & Urology News staff involved in the planning of this activity has no relevant financial relationships to disclose.

Disclosure of Unlabeled Use: This educational activity may contain discussion of approved and/or investigational uses of agents that are not indicated by the FDA. HME and Renal & Urology News do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of HME and Renal & Urology News. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimer: The content and views presented in this educational activity are those of the authors and do not necessarily reflect those of Haymarket Medical Education or Renal & Urology News. The authors have disclosed if there is any discussion of published and/or investigational uses of agents that are not indicated by the FDA in their presentations.The opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of Haymarket Medical Education or Renal & Urology News. Before prescribing any medicine, primary references and full prescribing information should be consulted. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. The information presented in this activity is not meant to serve as a guideline for patient management.

Method of Participation: There are no fees for participating in and receiving CME credit for this activity. During the period July 2014 through July 2015, participants must: 1) read the learning objectives and faculty disclosures, 2) study the educational activity, 3) complete the posttest and submit it online. Physicians may register at www.myCME.com/renalandurologynews, and 4) complete the evaluation form online.

A statement of credit will be issued only upon receipt of a completed activity evaluation form and a completed post-test with a score of 70% or better.