Hemodialysis News Archive

Clues to Spontaneous Resolution of Anemia in Hemodialysis Found

Clues to Spontaneous Resolution of Anemia in Hemodialysis Found

Restoration of iron homeostasis and normal hepcidin levels appears to play a key role in freeing hemodialysis patients from having to receive erythropoiesis-stimulating agents.

Anemia Severity Linked to LVH Risk in Pediatric Dialysis

Anemia Severity Linked to LVH Risk in Pediatric Dialysis

Time-averaged hemoglobin levels, not hemoglobin cycling, is associated with an increased risk of left ventricular hypertrophy in pediatric dialysis patients, a study found.

Hemodialysis Patient Death Risk Increased With Low Salt Intake

Hemodialysis Patient Death Risk Increased With Low Salt Intake

Salt intake below 6 g/day is associated with increased odds of all-cause and cardiovascular in patients on hemodialysis, Japanese study shows.

Hemodialysis Patients Aged 80+ Benefit From Switch to AVFs

Hemodialysis Patients Aged 80+ Benefit From Switch to AVFs

Elderly patients who start dialysis with a central venous catheter but convert to an arteriovenous fistula within the first year lower their death risk significantly.

Cardiovascular Event Rates Vary by Kidney Failure Cause

Cardiovascular Event Rates Vary by Kidney Failure Cause

Among US dialysis patients, cardiovascular event rates are highest in those with diabetic nephropathy and lowest among those with IgA nephropathy.

Phosphate Control May Reduce FGF23 Levels in HD

Phosphate Control May Reduce FGF23 Levels in HD

Patients on hemodialysis who achieved serum phosphate levels below 4.5 mg/dL experienced a decrease in intact fibroblast growth factor 23.

Phosphate Binders Lower Infection-Related Death Risk in HD

Phosphate Binders Lower Infection-Related Death Risk in HD

In a study, hemodialysis patients who used phosphate binders had up to a 44% decreased risk of dying from infection than those who did not use the drugs.

Cinacalcet Cessation Associated With Increases in PTH, Calcium

Cinacalcet Cessation Associated With Increases in PTH, Calcium

Researchers examined the effects of the end of public funding for the medication in Australia.

Parathyroidectomy for Secondary Hyperparathyroidism Improves Outcomes

Parathyroidectomy for Secondary Hyperparathyroidism Improves Outcomes

Surgical procedure can correct calcium and phosphorus abnormalities and improve coronary artery calcification, study finds.

Infection Risk Lower in Dialysis Patients With High, Normal Vitamin D

Infection Risk Lower in Dialysis Patients With High, Normal Vitamin D

Meta-analysis reveals a 39% decreased risk of any infection among patients on long-term dialysis who have high or normal vitamin D levels.

AV Access at Hemodialysis Initiation Less Likely Among Women

AV Access at Hemodialysis Initiation Less Likely Among Women

Study reveals 15% lower odds of arteriovenous access use at hemodialysis initiation among women vs men.

Obese HD Patients Need Less Erythropoietin to Treat Anemia

Obese HD Patients Need Less Erythropoietin to Treat Anemia

New study "adds to the evidence of obesity-associated advantages," researchers conclude.

Apixaban May Reduce Major Bleeding Risk in Dialysis Patients With AFib

Apixaban May Reduce Major Bleeding Risk in Dialysis Patients With AFib

Apixaban recipients had a 28% lower risk for major bleeding compared with patients treated with warfarin.

Few Hemodialysis Patients on Medicare Enroll in Hospice

Few Hemodialysis Patients on Medicare Enroll in Hospice

Patterns of use, timing of hospice similar among patients with diverse spending trajectories.

High FGF-23 Levels Linked to Lower Adiposity in Dialysis Patients

High FGF-23 Levels Linked to Lower Adiposity in Dialysis Patients

FGF-23 may have an effect on adipose tissue that contributes to an obesity paradox observed in patients with end-stage renal disease.

FDA Approves Noninvasive Devices for Arteriovenous Fistula Creation

FDA Approves Noninvasive Devices for Arteriovenous Fistula Creation

The devices use 1 or 2 catheters placed within the blood vessels to form AVFs in the arms of patients on hemodialysis.

Octogenarians Benefit From Nephrology Consult Before Dialysis Start

Octogenarians Benefit From Nephrology Consult Before Dialysis Start

In a Swiss study, patients aged 80 years or more were significantly less likely to die if they had a nephrology referral prior to initiating dialysis.

Pre-Dialysis Anemia Ups Mortality After Dialysis Start

Pre-Dialysis Anemia Ups Mortality After Dialysis Start

Patients with vs without anemia prior to starting hemodialysis (HD) were more likely to die despite achieving target hemoglobin levels at month 4 after HD initiation.

Moral Distress for Docs Providing Emergency-Only Hemodialysis

Moral Distress for Docs Providing Emergency-Only Hemodialysis

Docs describe burnout and emotional exhaustion; moral distress at seeing suffering and injustice.

Hemodialysis Patients on Medicare Often Referred Too Late to Hospice

Hemodialysis Patients on Medicare Often Referred Too Late to Hospice

Late hospice referral may limit the benefits patients receive, according to researchers.

Opioids Risky for Hemodialysis Patients

Opioids Risky for Hemodialysis Patients

Study links the pain relievers to altered mental status, fall, and fracture.

Predialysis Nephrology Care Associated With Lower AFib Risk

Predialysis Nephrology Care Associated With Lower AFib Risk

Older patients who had more frequent nephrology visits prior to initiating dialysis had a lower incidence of atrial fibrillation in the year after initiating dialysis compared with those who did not.

Intensive Phosphate Control May Reduce FGF23 in HD

Intensive Phosphate Control May Reduce FGF23 in HD

A serum phosphate control target of 4.5 mg/dL or below in hemodialysis patients was accompanied by a decline in fibroblast growth factor 23.

Fistula, Graft Angioplasty Success Linked to Aspirin Use

Fistula, Graft Angioplasty Success Linked to Aspirin Use

In a prospective study, aspirin users were more likely to have a successful outcome following PTA for venous stenoses in arteriovenous fistulas or grafts.

Cinacalcet Administration After Hemodialysis Safe, Effective

Cinacalcet Administration After Hemodialysis Safe, Effective

Control of parathyroid hormone did not differ markedly at 48 and 72 hours after in-center HD compared with 24 hours after daily oral administration of 30 mg cinacalcet.

Phosphate Binders Do Not Interfere With Vitamin D Therapy

Phosphate Binders Do Not Interfere With Vitamin D Therapy

Mean 25-hydroxyvitamin D levels did not differ significantly among groups receiving phosphate binders or dietary therapy.

Most Disliked Dialysis Dietary Restriction Is Limited Fluid Intake

Most Disliked Dialysis Dietary Restriction Is Limited Fluid Intake

In a survey, nearly one-third of hemodialysis patients said they disliked fluid restriction.

High Mean Corpuscular Volume Ups Hemodialysis Patient Death Risk

High Mean Corpuscular Volume Ups Hemodialysis Patient Death Risk

Study of 109,501 incidental HD patients reveals an association between high mean corpuscular volume and increased risk of all-cause, cardiovascular, and infection-related mortality.

Hemodialysis Patients With Low Selenium Levels More Likely to Die

Hemodialysis Patients With Low Selenium Levels More Likely to Die

Prospective study reveals that patients on hemodialysis whose blood selenium concentrations are in the lowest decile have a 3.4-fold higher odds of death.

Readmission Rates High for HD Patients After CVD Hospitalization

Readmission Rates High for HD Patients After CVD Hospitalization

In a study, the 30-day readmission rate for hemodialysis patients hospitalized for cardiovascular events was 34.2%.

Hemodialysis Induces Decline in Cerebral Blood Flow in Elderly

Hemodialysis Induces Decline in Cerebral Blood Flow in Elderly

Global CBF declined significantly by 10% from before the start to the end of hemodialysis.

Fresenius Names New Chief Medical Information Officer

Fresenius Names New Chief Medical Information Officer

Fresenius Medical Care North America has promoted Ahmad Sharif, MD, MPH, to Chief Medical Information Officer for North America.

Elevated ALP Linked With Mortality in Hemodialysis

Elevated ALP Linked With Mortality in Hemodialysis

Patients with the highest levels of serum alkaline phosphatase were more likely to die from infections and cardiovascular causes.

Nontraditional Risk Factors Predict Atherosclerotic Events in HD

Nontraditional Risk Factors Predict Atherosclerotic Events in HD

In hemodialysis patients, only non-traditional risk factors such as C-reactive protein predicted non-fatal myocardial infarction and other atherosclerotic events, researchers report.

Dialysis Withdrawal Preceded by Worsening Medical Condition

Dialysis Withdrawal Preceded by Worsening Medical Condition

New study finds an increase in medical events and institutionalization in the months leading up to dialysis withdrawal.

Method Gauges Transplant Referral Among Dialysis Facilities

Method Gauges Transplant Referral Among Dialysis Facilities

Standardized transplantation referral ratio shows most variation is due to within-facility characteristics.

Mortality High Among HD Patients Who Undergo Bladder Cancer Surgery

Mortality High Among HD Patients Who Undergo Bladder Cancer Surgery

Patients on hemodialysis who undergo radical cystectomy for bladder cancer have 30-day and 5-year mortality rates of 9.3% and 87.9%, respectively, study finds.

More Patients Starting Dialysis Are Still Employed

More Patients Starting Dialysis Are Still Employed

Employment low overall at 23 to 24% but increased 4.7% from 1996-2001 to 2008-2013.

Hemodialysis Patient Readmission Often Due to Pulmonary Edema

Hemodialysis Patient Readmission Often Due to Pulmonary Edema

Study finds that 44% of hospital readmissions among hemodialysis patients are related to pulmonary edema, with initial pulmonary edema-related hospitalization the strongest predictor for readmission due to the condition.

Obstructive Sleep Apnea, Significant Interdialytic Weight Gain Linked

Obstructive Sleep Apnea, Significant Interdialytic Weight Gain Linked

Researchers find a higher proportion of hemodialysis patients with interdialytic weight gain greater than 2 kg among patients with versus without obstructive sleep apnea.

Urologic Cancer Risk Higher in Kidney Failure Patients

Urologic Cancer Risk Higher in Kidney Failure Patients

Patients with end-stage renal disease (ESRD) have a 6-fold and 4.4-fold increased risk of kidney cancer and urothelial cancers, respectively, than individuals without ESRD.

Undocumented Immigrants Receiving Emergency HD More Likely to Die

Undocumented Immigrants Receiving Emergency HD More Likely to Die

The 5-year relative risk for mortality was 14-fold higher for undocumented immigrants receiving emergency-only versus standard hemodialysis.

Hemodialysis CRBSI Outcomes Unaffected by Distance to Nephrologists

Hemodialysis CRBSI Outcomes Unaffected by Distance to Nephrologists

Canadian study reveals no significant effect of driving distance to a nephrology practice on the rate and appropriate management of catheter-related bloodstream infections.

Shift in HIV-Associated Kidney Disease Characterized

Shift in HIV-Associated Kidney Disease Characterized

Antiretroviral therapies have prolonged the survival of HIV patients, but the drugs can have adverse effects on the kidneys.

Calciphylaxis in CKD Patients Linked to Hypercoagulable Conditions

Calciphylaxis in CKD Patients Linked to Hypercoagulable Conditions

In patients with stage 5 chronic kidney disease, lupus anticoagulant and combined thrombophilia occur more frequently in those with versus without calciphylaxis, case-control study shows.

Darbepoetin Alfa Safe for Pediatric CKD Patients With Anemia

Darbepoetin Alfa Safe for Pediatric CKD Patients With Anemia

Researchers tested once weekly and biweekly administration of darbepoetin alfa in children aged 1 to 18 years not previously treated with an erythropoiesis-stimulating agent.

Residual Renal Function Not Linked to ESA Requirements

Residual Renal Function Not Linked to ESA Requirements

Researchers find no significant difference in the median erythropoietin resistance index between patients with versus without residual renal function.

High ESA and Iron Doses Up CVD, Death Risk in Hemodialysis Patients

High ESA and Iron Doses Up CVD, Death Risk in Hemodialysis Patients

High doses of iron are associated with a significantly higher risk of cardiovascular disease, regardless of the dose of erythropoiesis-stimulating agent.

Hemodialysis, Peritoneal Dialysis Offer Similar Survival

Hemodialysis, Peritoneal Dialysis Offer Similar Survival

Effect of either dialysis modality on survival does not vary over time, study finds.

IV Iron, Erythropoietin Equally Effective for Anemia in HD Patients

IV Iron, Erythropoietin Equally Effective for Anemia in HD Patients

Intravenous iron and erythropoietin produced a similar hemoglobin response among hemodialysis patients with moderate anemia.

Elevated PTH Tied to Arteriovenous Fistula Maturation Failure

Elevated PTH Tied to Arteriovenous Fistula Maturation Failure

Secondary hyperparathyroidism may have a detrimental effect on successful arteriovenous fistula creation, researcher says.

Low Uric Acid Ups Death Risk in Hemodialysis Patients

Low Uric Acid Ups Death Risk in Hemodialysis Patients

The 5-year survival rates was 80.7% for patients in the lowest quartile of serum uric acid at HD initiation versus 89.6% for those in the highest quartile.

Abnormal Sodium Levels Up Bacteremia Risk in Dialysis Patients

Abnormal Sodium Levels Up Bacteremia Risk in Dialysis Patients

Study reveals 2-fold higher incidence of bacteremia among dialysis patients with low and high serum sodium levels.

Waist-to-hip Ratio Predicts CV Mortality in Hemodialysis Patients

Waist-to-hip Ratio Predicts CV Mortality in Hemodialysis Patients

Each 0.1 increase in WHR is associated with a 1.7-fold increased risk of cardiovascular death.

Veterans With PTSD Less Likely to Die After Starting Dialysis

Veterans With PTSD Less Likely to Die After Starting Dialysis

Patients with post-traumatic stress disorder had an 11% lower death risk 1 year after initiating dialysis than those without the disorder, study finds.

'Clinically Negligible' Residual Kidney Function Still Beneficial

'Clinically Negligible' Residual Kidney Function Still Beneficial

Even at very low levels, residual kidney function in hemodialysis patients clears uremic solutes.

Hypertension, Diabetes at Hemodialysis Initiation Increasing

Hypertension, Diabetes at Hemodialysis Initiation Increasing

From 1995 to 2015, the prevalence of hypertension and diabetes among patients starting hemodialysis increased from 67.9% to 87.6% and from 43.1% to 59.6%, respectively.

Intensive Home HD, Deceased-Donor Transplants Offer Similar Survival

Intensive Home HD, Deceased-Donor Transplants Offer Similar Survival

After adjusting for confounders, patients on intensive home hemodialysis and recipients of deceased-donor kidneys showed no significant difference in death risk

Post-Dialysis Survival Odds Better After CABG vs PCI

Post-Dialysis Survival Odds Better After CABG vs PCI

US veterans who underwent coronary artery bypass grafting versus percutaneous coronary intervention prior to starting dialysis had a 28% lower risk of death.

Risk of First Infection-Related Hospitalization Higher With HHD

Risk of First Infection-Related Hospitalization Higher With HHD

Hemodialysis patients who have fistula are 24% more likely to experience a first infection-related hospitalization if they dialyze at home rather than in a dialysis center.

TAVR Ups Risk of ESRD, Death for Advanced CKD Patients

TAVR Ups Risk of ESRD, Death for Advanced CKD Patients

Transcatheter aortic valve replacement increases the risk of requiring renal replacement therapy and the risk of death among patients with stage 4 or 5 CKD.

Dialysis Nurses Volunteer for Puerto Rico Relief Effort

Dialysis Nurses Volunteer for Puerto Rico Relief Effort

Three weeks after Hurricane Maria ravaged the island, Fresenius Kidney Care is flying dialysis nurses to relieve staff and help patients at the company's 27 operational dialysis centers.

High Rates of Infective Endocarditis Found Among ESRD Patients

High Rates of Infective Endocarditis Found Among ESRD Patients

Hemodialysis patients had higher rates of infective endocarditis than peritoneal dialysis and kidney transplant patients.

Discharged Dialysis Patients Commonly Readmitted for Different Reasons

Discharged Dialysis Patients Commonly Readmitted for Different Reasons

In 80% of readmissions, the primary diagnoses differed from initial hospitalization.

Health Beliefs About Salt Intake Low Among Dialysis Patients

Health Beliefs About Salt Intake Low Among Dialysis Patients

Score for subscale of perceived seriousness for no reduction of salt intake higher in transplant patients.

Opioid Overprescribing, Overdosing Common in Dialysis

Opioid Overprescribing, Overdosing Common in Dialysis

High-risk dialysis population also subject to the risks of long-term opioid use.

Pruritus in Hemodialysis Patients Underestimated, Undertreated

Pruritus in Hemodialysis Patients Underestimated, Undertreated

Among hemodialysis patients always or nearly always bothered by itchy skin, 17% did not report their symptoms to a health care provider and 18% used no treatment for the condition.

Arteriovenous Fistulas Not Always the Best Option

Arteriovenous Fistulas Not Always the Best Option

Despite low infection rates, AVFs have a high risk of maturation failure and abandonment.

Fewer Patients Require Dialysis After TAVI

Fewer Patients Require Dialysis After TAVI

From 2007/2008 to 2013/2014, the proportion of patients newly needing dialysis after TAVI decreased from 6.1% to 2.3%.

For Treating Uremic Pruritus, Evidence is Strongest for Gabapentin

For Treating Uremic Pruritus, Evidence is Strongest for Gabapentin

Except for gabapentin, evidence for 38 other treatments is weak and limited by small studies with a high risk of bias, new review finds.

Venous Thromboembolism Risk Elevated in Dialysis Patients

Venous Thromboembolism Risk Elevated in Dialysis Patients

VTE is more common among dialysis patients than in the general population, and the risk is highest in the first 6 months after dialysis initiation.

Women Less Likely to Initiate Hemodialysis With an AV Fistula

Women Less Likely to Initiate Hemodialysis With an AV Fistula

The odds of starting hemodialysis with an arteriovenous fistula are 31% lower for women compared with men.

Hypothyroidism Tied to Worse Quality of Life for HD Patients

Hypothyroidism Tied to Worse Quality of Life for HD Patients

High thyrotropin levels were associated with worse measures of energy/fatigue and physical functioning.

Optimal Iron Status for Hemodialysis Patients Reported

Optimal Iron Status for Hemodialysis Patients Reported

Japanese researchers conclude that a serum ferritin level below 90 ng/mL and TSAT of 20% or higher was optimal for achieving a hemoglobin level of 10 g/dL or higher.

HD Catheters Linked With Highest Rate of Bloodstream Infections

HD Catheters Linked With Highest Rate of Bloodstream Infections

Nearly 70% of access-related bloodstream infections occurred in hemodialysis patients with central venous catheters.

Guidelines for CKD Mineral and Bone Disorder Updated

Guidelines for CKD Mineral and Bone Disorder Updated

Among other changes, the new KDIGO guidelines highlight the potential dangers of hypercalcemia.

RBC Distribution Width, Dialysis Patient Mortality Linked

RBC Distribution Width, Dialysis Patient Mortality Linked

As red blood cell distribution width increases, so does the risk of death from any cause.

Early Hospital Readmission Ups Hemodialysis Patient Mortality Risk

Early Hospital Readmission Ups Hemodialysis Patient Mortality Risk

Patients who are readmitted within 30 days of discharge are approximately twice as likely to die in the following year.

Low Albumin Tied With Early Death in Patients Starting Dialysis

Low Albumin Tied With Early Death in Patients Starting Dialysis

The overall percentage of death during the one-year follow-up was 6.87%, with 64% of deaths occurring during the first 6 months.

Residual Kidney Function Predicts Mortality in CKD-MBD

Residual Kidney Function Predicts Mortality in CKD-MBD

In a study of hemodialysis patients, mortality risk increased along with phosphorus level, particularly among patients with higher residual renal urea clearance.

Post-Cystectomy Deaths Among HD Patients Seldom Due to Cancer

Post-Cystectomy Deaths Among HD Patients Seldom Due to Cancer

Following radical cystectomy for bladder cancer, end-stage renal disease patients are 3-4 times more likely to die from causes other than cancer.

Topically Applied Drug May Improve Hemodialysis Fistula Survival

Topically Applied Drug May Improve Hemodialysis Fistula Survival

In a study, vonapanitase did not improve primary patency compared with placebo, but did improve secondary patency and fistula use for hemodialysis.

Sudden Cardiac Death Rate Remains High Among Hemodialysis Patients

Sudden Cardiac Death Rate Remains High Among Hemodialysis Patients

Among hemodialysis patients, sudden cardiac death accounted for 12% more cardiovascular-related mortalities in 2013 than in 2009.

Insurance Type Affects Initial Dialysis Modality Choice

Insurance Type Affects Initial Dialysis Modality Choice

ESRD patients aged 60-64 years with no insurance or who are on Medicaid are less likely to initiate peritoneal dialysis.

Triferic Pharmacokinetics Characterized

Triferic Pharmacokinetics Characterized

Ferric pyrophosphate citrate delivered via dialysate or intravenously rapidly donates iron to transferrin and is rapidly cleared from the circulation.

Unplanned Readmissions of Hemodialysis Patients Probed

Unplanned Readmissions of Hemodialysis Patients Probed

Nearly a quarter of hospitalizations are followed by readmission within 30 days for non-elective reasons.

Hemodialysis Patient Hospitalization Rates Declining

Hemodialysis Patient Hospitalization Rates Declining

Study documents an upswing in emergency department visits and observation stays.

Study Suggests Colon Cancer Overscreening in Dialysis Patients

Study Suggests Colon Cancer Overscreening in Dialysis Patients

Patients in the lowest quartile of mortality risk were more likely to be screened for colon cancer than those in the highest quartile.

Higher Mortality Found After RFA in ESRD Dialysis Patients

Higher Mortality Found After RFA in ESRD Dialysis Patients

In-hospital mortality following RFA was higher in older, dialyzed ESRD patients than in non dialyzed patients.

Early Predialysis Nephrology Care May Prevent CV Events

Early Predialysis Nephrology Care May Prevent CV Events

Patients with early and frequent nephrology visits before dialysis initiation had about a 10% lower risk for major adverse cardiovascular events.

Undocumented Immigrants With ESRD Face Poor Health Care Access

Undocumented Immigrants With ESRD Face Poor Health Care Access

ESRD sufferers in the US illegally seek hospital emergency departments with distressing symptoms.

Nephrologists Not Prescribing Antidepressants to Dialysis Patients

Nephrologists Not Prescribing Antidepressants to Dialysis Patients

Patients on chronic hemodialysis with depression are frequently not interested in modifying or initiating antidepressant treatment, commonly attributing their depression to a recent acute event, chronic illness, or dialysis.

Off-Target CKD-MBD Biomarkers Prognostic for Adverse Outcomes

Off-Target CKD-MBD Biomarkers Prognostic for Adverse Outcomes

Dialysis facilities with the least control of PTH, Ca, and P had the greatest risks.

Frequent Hemodialysis Improves Health-Related QoL

Frequent Hemodialysis Improves Health-Related QoL

Patients feel better and recovery times are shorter with 6 hemodialysis sessions per week rather than 3, researchers report.

Many Hemodialysis Patients Have Sleep Difficulties

Many Hemodialysis Patients Have Sleep Difficulties

Participants experienced poor sleep quality, increased daytime sleepiness, as well as restless leg syndrome due to maintenance hemodialysis.

Calciphylaxis Linked to Low Vitamin K

Calciphylaxis Linked to Low Vitamin K

An enzyme that inhibits vascular calcification depends on the vitamin for conversion to its active form.

AVF Failure Not Improved By Fish Oil Supplements, Low-Dose Aspirin

AVF Failure Not Improved By Fish Oil Supplements, Low-Dose Aspirin

Researchers reported a 47% AVF failure rate for both fish oil and placebo recipients.

Daily Walking Improves Physical, Mental Wellbeing of Dialysis Patients

Daily Walking Improves Physical, Mental Wellbeing of Dialysis Patients

The study shows that simple, home-based exercise programs hold potential for improving physical functioning in dialysis patients.

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