Generic Name and Formulations:
Estazolam 1mg, 2mg; scored tabs.
Various generic manufacturers
Indications for Estazolam:
Short-term treatment of insomnia.
Initially 1mg at bedtime. May increase to 2mg nightly. Small or debilitated elderly: initially 0.5mg.
<18yrs: not recommended.
Concomitant ketoconazole, itraconazole. Pregnancy (Cat.X).
Drug or alcohol abuse. Suicidal tendencies. Depression. Renal, hepatic, or respiratory impairment. Avoid abrupt cessation after prolonged use. Elderly. Debilitated. Nursing mothers: not recommended.
Potentiates CNS depression with alcohol, other CNS depressants. Caution with CYP3A inhibitors (eg, nefazodone, fluvoxamine, cimetidine, diltiazem, isoniazid, other macrolides): consider dose reduction.
CNS depression, complex sleep-related behaviors (eg, sleep-driving), hypokinesia, dizziness, incoordination, confusion, constipation, anxiety, paradoxical excitement; anaphylaxis, angioedema.
Formerly known under the brand name Prosom.
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