End-Stage Renal Disease News Archive

Death, CVD, Type 2 Diabetes Not Increased for Living Kidney Donors

Death, CVD, Type 2 Diabetes Not Increased for Living Kidney Donors

Increased risks for ESRD, preeclampsia, although absolute risk of these outcomes remains low.

Study: ESRD Risk in Type 1 Diabetes Pts Has Declined

Study: ESRD Risk in Type 1 Diabetes Pts Has Declined

Relative risk of end-stage renal disease was 0.13 in those diagnosed in 1995-2011 versus 1965-1979.

Early RRT for Acute Kidney Injury Not Superior

Early RRT for Acute Kidney Injury Not Superior

Early and late initiation of renal replacement therapy for AKI in critically ill patients are associated with similar long-term risks of death, chronic kidney disease, and end-stage renal disease.

Hemodialysis Patient Readmission Often Due to Pulmonary Edema

Hemodialysis Patient Readmission Often Due to Pulmonary Edema

Study finds that 44% of hospital readmissions among hemodialysis patients are related to pulmonary edema, with initial pulmonary edema-related hospitalization the strongest predictor for readmission due to the condition.

Urologic Cancer Risk Higher in Kidney Failure Patients

Urologic Cancer Risk Higher in Kidney Failure Patients

Patients with end-stage renal disease (ESRD) have a 6-fold and 4.4-fold increased risk of kidney cancer and urothelial cancers, respectively, than individuals without ESRD.

Kidney Failure Risk Equation Validated in Children

Kidney Failure Risk Equation Validated in Children

The tool demonstrated strong discrimination for ESRD risk in children over the short term.

Undocumented Immigrants Receiving Emergency HD More Likely to Die

Undocumented Immigrants Receiving Emergency HD More Likely to Die

The 5-year relative risk for mortality was 14-fold higher for undocumented immigrants receiving emergency-only versus standard hemodialysis.

Excess Death Risk in ESRD Has Declined

Excess Death Risk in ESRD Has Declined

Decrease in excess risk of all-cause mortality from 1995 to 2013 for those with end-stage renal disease.

Calciphylaxis in CKD Patients Linked to Hypercoagulable Conditions

Calciphylaxis in CKD Patients Linked to Hypercoagulable Conditions

In patients with stage 5 chronic kidney disease, lupus anticoagulant and combined thrombophilia occur more frequently in those with versus without calciphylaxis, case-control study shows.

Hemodialysis, Peritoneal Dialysis Offer Similar Survival

Hemodialysis, Peritoneal Dialysis Offer Similar Survival

Effect of either dialysis modality on survival does not vary over time, study finds.

Kidney Risks Differ Among Oral Anticoagulant Drugs for AFib

Kidney Risks Differ Among Oral Anticoagulant Drugs for AFib

Dabigatran and rivaroxaban were associated with lower risks of adverse renal outcomes compared with warfarin.

ESRD Risk Low for Type 1 Diabetes

ESRD Risk Low for Type 1 Diabetes

Findings among a large study of Norwegian children followed for 40-plus years.

End-Stage Renal Disease From Diabetes Declined in US

End-Stage Renal Disease From Diabetes Declined in US

2000 to 2014 saw decrease in incidence of ESRD with diabetes listed as the primary cause.

Proton Pump Inhibitor Use May Up CKD, ESRD

Proton Pump Inhibitor Use May Up CKD, ESRD

Risk for both chronic kidney disease, end-stage renal disease higher with proton pump inhibitor use.

Low Urinary Uromodulin Predicts Worse Kidney Outcomes

Low Urinary Uromodulin Predicts Worse Kidney Outcomes

Patients in the lowest quartiles of urinary uromodulin had increased risks of end-stage renal disease and rapid kidney function decline.

Anemia Raises ESRD Risk in Patients With Chronic Kidney Disease

Anemia Raises ESRD Risk in Patients With Chronic Kidney Disease

In a study, end-stage renal disease was 31% more likely to develop in CKD patients with versus without anemia.

ESRD Frequently Follows Dialysis-Dependent AKI

ESRD Frequently Follows Dialysis-Dependent AKI

In a study, end-stage renal disease developed in 56% of patients discharged from a hospital with acute kidney injury requiring dialysis.

Girls With ESRD More Likely to Die

Girls With ESRD More Likely to Die

Girls with end-stage renal disease had 35% greater risk for death than boys.

ESRD Linked to Recurrent Symptomatic Kidney Stones

ESRD Linked to Recurrent Symptomatic Kidney Stones

Recurrent, but not first-time, symptomatic kidney stone formers are at elevated risk for end-stage renal disease and death.

Most Type 1 Diabetes Patients Have Kidney Disease

Most Type 1 Diabetes Patients Have Kidney Disease

Incidence of end-stage renal disease has declined but affects substantial portion of long-term T1D patients.

Glycemic Control Intensity Does Not Influence ESRD, Mortality

Glycemic Control Intensity Does Not Influence ESRD, Mortality

End-stage renal disease developed in similar proportions of diabetics regardless of whether they had intensive or standard glycemic control.

Dialysis Nurses Volunteer for Puerto Rico Relief Effort

Dialysis Nurses Volunteer for Puerto Rico Relief Effort

Three weeks after Hurricane Maria ravaged the island, Fresenius Kidney Care is flying dialysis nurses to relieve staff and help patients at the company's 27 operational dialysis centers.

High Rates of Infective Endocarditis Found Among ESRD Patients

High Rates of Infective Endocarditis Found Among ESRD Patients

Hemodialysis patients had higher rates of infective endocarditis than peritoneal dialysis and kidney transplant patients.

Air Pollution May Lead to CKD, ESRD

Air Pollution May Lead to CKD, ESRD

Study finds link between particulate matter and renal function.

Pruritus in Hemodialysis Patients Underestimated, Undertreated

Pruritus in Hemodialysis Patients Underestimated, Undertreated

Among hemodialysis patients always or nearly always bothered by itchy skin, 17% did not report their symptoms to a health care provider and 18% used no treatment for the condition.

Chronic Kidney Disease Raises Tinnitus Risk

Chronic Kidney Disease Raises Tinnitus Risk

Tinnitus is 3-fold more likely to develop in patients with versus without chronic kidney disease, new study shows.

Olfactory Deficits, Malnutrition Markers Linked in CKD, ESRD Patients

Olfactory Deficits, Malnutrition Markers Linked in CKD, ESRD Patients

Pilot study suggests intranasal theophylline may be worth further investigation as a treatment.

Hip Fracture Rates Falling Among ESRD Patients

Hip Fracture Rates Falling Among ESRD Patients

From 2003 to 2011 there was a 26.7% decrease in in-hospital mortality rate after hip fracture.

Biomarker May Identify High-risk IgAN Patients

Biomarker May Identify High-risk IgAN Patients

Gd-IgA1 level may represent a useful biomarker for risk stratification.

HIV-Infected Living Kidney Donors Have Low ESRD Risk

HIV-Infected Living Kidney Donors Have Low ESRD Risk

HIV-positive individuals with well-controlled disease and no comorbidities have a low risk of ESRD following living kidney donation.

ESRD Risk Higher Among Black, Male Living Kidney Donors

ESRD Risk Higher Among Black, Male Living Kidney Donors

The researchers found that black race and male sex correlated with increased risk of ESRD in donors.

Testosterone Replacement May Delay CKD Progression

Testosterone Replacement May Delay CKD Progression

Study demonstrates decreased risk of end-stage renal disease and all-cause mortality.

Reduced Kidney Function a Major Cause of Cardiovascular Deaths

Reduced Kidney Function a Major Cause of Cardiovascular Deaths

Reduced glomerular filtration rate ranked similarly to high total cholesterol as a risk factor for disability-adjusted life years.

No Adverse Outcomes Following Bundling

No Adverse Outcomes Following Bundling

Action taken to mitigate risks associated with ESA use and changes in payment policy did not result in a relative increase in death or major cardiovascular events.

Higher Mortality Found After RFA in ESRD Dialysis Patients

Higher Mortality Found After RFA in ESRD Dialysis Patients

In-hospital mortality following RFA was higher in older, dialyzed ESRD patients than in non dialyzed patients.

Initiation of Renal Replacement Therapy Affects Mental State

Initiation of Renal Replacement Therapy Affects Mental State

The initiation of RRT has a strong impact on HRQL in comparison with a reference population and with other stages of CKD.

Creatinine Rise After RAS Blockade May Up Cardiorenal Risks

Creatinine Rise After RAS Blockade May Up Cardiorenal Risks

Study documents higher risks even when creatinine increases are less than 30%, the guideline-recommended threshold for stopping treatment.

Sickle Cell Trait in Blacks Increases ESRD Risk

Sickle Cell Trait in Blacks Increases ESRD Risk

Carriers have a 2-fold higher risk of end-stage renal disease compared with non-carriers, study finds.

ESRD Renal Recovery Uptick Reported

ESRD Renal Recovery Uptick Reported

Use of bioimpedance spectroscopy to assess volume depletion could be a factor, researchers say.

Advanced CKD Patients May Benefit From Dietary Therapy

Advanced CKD Patients May Benefit From Dietary Therapy

Few nephrologists currently prescribe nutritional regimens for their patients approaching the need for renal replacement therapy or who already require it.

Hospital Readmission Common With Heart Failure

Hospital Readmission Common With Heart Failure

Among the etiologies of readmission, cardiac causes including heart failure and coronary artery disease were most common.

Elemental Calcium Intake High With Calcium-Based Binder Use

Elemental Calcium Intake High With Calcium-Based Binder Use

In a study, 25.8% and 37.8% of calcium acetate and calcium carbonate users, respectively, exceeded the maximum recommended daily intake.

Undocumented Immigrants With ESRD Face Poor Health Care Access

Undocumented Immigrants With ESRD Face Poor Health Care Access

ESRD sufferers in the US illegally seek hospital emergency departments with distressing symptoms.

Metabolites Linked to Faster Renal Decline, Failure in Type 1 Diabetes

Metabolites Linked to Faster Renal Decline, Failure in Type 1 Diabetes

Serum levels of 7 modified metabolites were associated with renal function decline and time to ESRD.

ESRD Risk Factors in IgAN Patients Identified

ESRD Risk Factors in IgAN Patients Identified

Predictors of renal failure within 10 years include Oxford M1 disease and low eGFR at biopsy.

ESRD From Diabetes Declining in Native Americans

ESRD From Diabetes Declining in Native Americans

The Indian Health Service has made progress by applying population health and team-based approaches to diabetes and kidney care.

ESRD Risk Higher in SLE Patients Hospitalized for Infections

ESRD Risk Higher in SLE Patients Hospitalized for Infections

End-stage renal disease is 5-fold more likely to develop in patients with 3 or more infection-related hospitalizations versus none.

Survival Rates Differ by Race for Pediatric ESRD Patients

Survival Rates Differ by Race for Pediatric ESRD Patients

Non-Hispanic black children had a 36% higher risk of death and Hispanic children had a 34% lower risk of death than non-Hispanic white children.

Hypo- , Hyperkalemia Linked to ESRD

Hypo- , Hyperkalemia Linked to ESRD

The risks of death from any cause were elevated by 22% and 31% for individuals with serum potassium levels of 5.5 mmol/L and 3.2 mmol/L, respectively, compared with 4.2 mmol/L.

Low, High Uric Acid Ups Post-ESRD Death Risk

Low, High Uric Acid Ups Post-ESRD Death Risk

Levels of 10 mg/dL or higher and below 6 mg/dL predicted approximately 50% higher death risk in the 3 months after dialysis initiation.

Constipation Associated With CKD, ESRD Risk

Constipation Associated With CKD, ESRD Risk

Since constipation is common, the study findings may be important for public health.

ESRD Uncommon Among Type 1 Diabetes Patients

ESRD Uncommon Among Type 1 Diabetes Patients

The researchers found that 4.6% of participants developed ESRD and 20.6% died during 30 years of follow-up.

ESRD Linked to Diet Soda Consumption

ESRD Linked to Diet Soda Consumption

The risk of end-stage renal disease was 83% higher for those who drank more than 7 glasses of diet soft drinks weekly.

Dialysis Patient Outcomes Not Worse After Bundling, ESA Label Changes

Dialysis Patient Outcomes Not Worse After Bundling, ESA Label Changes

Study finds no increased risk of major adverse cardiovascular events and death.

Absent Pulses Up Risk of Vascular Events, ESRD in Type 2 Diabetes

Absent Pulses Up Risk of Vascular Events, ESRD in Type 2 Diabetes

Every additional absent dorsalis pedis or posterior tibial pulse linked to increased risk of all outcomes.

Systolic Blood Pressure Variability Linked to ESRD, Mortality

Systolic Blood Pressure Variability Linked to ESRD, Mortality

Increased SBP variability tied to mortality, coronary heart disease, stroke, end-stage renal disease

High CRP Ups Kidney Failure Risk in Diabetic CKD Patients With Anemia

High CRP Ups Kidney Failure Risk in Diabetic CKD Patients With Anemia

End-stage renal disease is 32% more likely to develop in patients with C-reactive protein levels of 6.9 mg/L or higher vs 3.0 mg/L or lower.

Check Hemodialysis Patients for Anxiety Disorders, Study Suggests

Check Hemodialysis Patients for Anxiety Disorders, Study Suggests

Screening strategies are needed, as is further research on appropriate therapeutic approach.

Dialysis Adoption by US Veterans Outpaces Other Nations

Dialysis Adoption by US Veterans Outpaces Other Nations

In a study, 85.5% of advanced CKD patients opted for renal replacement therapy.

ESRD Patients Visit Emergency Departments More Frequently

ESRD Patients Visit Emergency Departments More Frequently

More than half of newly diagnosed ESRD patients visit the emergency department during their first year of treatment.

Fracture Risk Factors in Transplant Patients ID'd

Fracture Risk Factors in Transplant Patients ID'd

Major fractures included the proximal humerus, forearm, hip, and clinical vertebral fractures.

Glomerulonephritis Raises End-Stage Renal Disease Risk

Glomerulonephritis Raises End-Stage Renal Disease Risk

Data suggest primary GN is more likely than secondary GN to result in end-stage renal disease.

No Kidney Failure Improvement With Vasopressin in Septic Shock

No Kidney Failure Improvement With Vasopressin in Septic Shock

No improvement in kidney failure-free days versus norepinephrine in adults with septic shock.

Higher Red Meat Intake Raises Kidney Failure Risk

Higher Red Meat Intake Raises Kidney Failure Risk

Highest vs lowest quartile of intake is associated with a 40% increased risk.

Antihypertensive Drug Use in Dialysis Transition May Need Improvement

Antihypertensive Drug Use in Dialysis Transition May Need Improvement

Only 40% of older patients transitioning to maintenance dialysis were on renin-angiotensin system blockade.

Higher Allopurinol Dose Protects Elderly From Renal Failure

Higher Allopurinol Dose Protects Elderly From Renal Failure

A higher allopurinol dose was protective against renal failure in elderly allopurinol recipients.

Lupus Nephritis ESRD Has Worse Outcomes

Lupus Nephritis ESRD Has Worse Outcomes

Researchers find an increased risk of death among patients.

Low Midlife Fitness May Predict Future CKD

Low Midlife Fitness May Predict Future CKD

High vs. low fitness levels in midlife lowered CKD risk in later life by 34%.

Higher Cancer Risk in Dialysis Patients Confirmed

Higher Cancer Risk in Dialysis Patients Confirmed

The risk is most elevated among individuals aged 44 years or younger.

CABG Better Than PCI in End-Stage Renal Disease

CABG Better Than PCI in End-Stage Renal Disease

Updated review and meta-analysis show beneficial effect for CABG for long-term mortality.

Smelling Ability Impaired in Renal Disease Patients

Smelling Ability Impaired in Renal Disease Patients

Finding suggests that olfactory deficits may contribute to nutritional impairment in patients with chronic and end-stage renal disease.

Partial Nephrectomy Protects Against ESRD

Partial Nephrectomy Protects Against ESRD

Nephron-sparing surgery decreased the risk of end-stage renal disease by 60% in select patients.

Premature Tooth Loss Common Among ESRD Patients

Premature Tooth Loss Common Among ESRD Patients

Findings from a small study suggest that periodontal disease may be a relevant contributing factor.

Higher ESRD Risk in Blacks Not Due Solely to Genetic Variants

Higher ESRD Risk in Blacks Not Due Solely to Genetic Variants

African Americans with and without a high-risk genotype experience similar kidney function decline.

Intensive Glucose Control May Result in Lasting ESRD Prevention

Intensive Glucose Control May Result in Lasting ESRD Prevention

In-trial reduction in risk of ESRD seen in ADVANCE trial persists after 9.9 years of follow-up.

Conservative Management Reasonable for Older Patients With ESRD

Conservative Management Reasonable for Older Patients With ESRD

Researchers suggest conservative care may be suitable option for some patients over 80.

Study Questions Blood Pressure Target for Diabetes Patients

Study Questions Blood Pressure Target for Diabetes Patients

A new large scale study found that depending on baseline systolic blood pressure (SBP) level, the use of antihypertensive medication led to different outcomes in patients with diabetes.

Statins Do Not Reduce Kidney Failure Risk

Statins Do Not Reduce Kidney Failure Risk

Pre-dialysis CKD patients who took statins did experience a modest reduction in proteinuria and kidney function decline.

Adverse Renal Outcomes Linked to Blood Pressure Variability

Adverse Renal Outcomes Linked to Blood Pressure Variability

Greater visit-to-visit variability in systolic blood pressure is associated with a higher risk of ESRD or a 50% or greater decrease in eGFR.

Abrupt Pre-Dialysis Kidney Function Decline Predicts Early Death

Abrupt Pre-Dialysis Kidney Function Decline Predicts Early Death

Study finds a 3-folder greater risk of early death within a year of hemodialysis initiation.

ESRD Anemia Responds to Investigational Oral Drug

ESRD Anemia Responds to Investigational Oral Drug

In a phase 2 trial, roxadustat maintained hemoglobin levels over 19 weeks as well as epoetin alfa.

Very Low-Protein Diet With Ketoanalogue May Slow CKD Progression

Very Low-Protein Diet With Ketoanalogue May Slow CKD Progression

Four patients would need to adhere to diet to avoid primary end point in per-protocol analysis.

Factors Influencing the Timing of Dialysis Initiation

Factors Influencing the Timing of Dialysis Initiation

Factors include care practices of physicians, sources of momentum, patient-physician interactions.

Online Tool Helps Predict ESRD in CKD Patients

Online Tool Helps Predict ESRD in CKD Patients

New risk calculator estimates who will need dialysis in 2 to 5 years.

Diabetic, Non-Diabetic ESRD Patients at High Risk for Hypoglycemia

Diabetic, Non-Diabetic ESRD Patients at High Risk for Hypoglycemia

Severe hypoglycemia may result in changes in mental state, seizures, arrhythmias, coma, and death.

PSA Screening May Harm ESRD Patients Awaiting Transplant

PSA Screening May Harm ESRD Patients Awaiting Transplant

Screening not linked to improved patient survival after transplant; may delay time to listing, transplant.

Current eGFR Better for ESRD Prediction

Current eGFR Better for ESRD Prediction

It has a stronger association with future end-stage renal disease risk than past eGFR decline, large study shows.

ACE Inhibitors May Be a Better Option for CKD Patients

ACE Inhibitors May Be a Better Option for CKD Patients

The medications are associated with reduced odds of kidney failure and death compared with angiotensin II receptor blockers.

ESRD and Treatments May Raise Cancer Risk

ESRD and Treatments May Raise Cancer Risk

Dialysis, organ transplant may increase odds for certain types of cancer.

Long-Term Statin Therapy Improves Outcomes in CKD Patients With CAD

Long-Term Statin Therapy Improves Outcomes in CKD Patients With CAD

Long-term statin treatment cut the rates of major adverse cardiovascular events by 20.5%, all-cause mortality by 28.6%.

Urinary Potassium Linked to Lower ESRD, CVD Risk in Diabetes

Urinary Potassium Linked to Lower ESRD, CVD Risk in Diabetes

Higher urinary potassium excretion, not sodium excretion, tied to lower risk of primary end point.

High Dietary Sodium, Potassium Raise CKD Progression Risk

High Dietary Sodium, Potassium Raise CKD Progression Risk

Researchers also observe an increased risk of early death from any cause.

Lower Pre-ESRD Hemoglobin Predicts Better Dialysis Patient Survival

Lower Pre-ESRD Hemoglobin Predicts Better Dialysis Patient Survival

Having hemoglobin 9-11 g/dL prior to dialysis provided the best life expectancy.

Higher Triglycerides Linked With Lower Mortality in Early Dialysis

Higher Triglycerides Linked With Lower Mortality in Early Dialysis

Veteran patients with levels below 100 mg/dL had a 26% higher risk of mortality compared with patients with triglyceride levels of 150-200 mg/dL.

ESRD Risk Can Be Estimated in Living Kidney Donors

ESRD Risk Can Be Estimated in Living Kidney Donors

Multiple demographic and health characteristics can estimate projected long-term risk.

High Uric Acid Raises ESRD Risk

High Uric Acid Raises ESRD Risk

The highest vs. lowest quartile of serum uric acid is associated with a 3.4-fold increased risk of end-stage renal disease.

Early Dialysis Withdrawal on the Rise

Early Dialysis Withdrawal on the Rise

Withdrawal rates are highest in the first few months after dialysis initiation.

Mortality Risk Remains With Type 2 Diabetes

Mortality Risk Remains With Type 2 Diabetes

Risks vary per age, glycemic control, and renal complications.

HD Patient Survival Similar with Grafts, Fistulas

HD Patient Survival Similar with Grafts, Fistulas

No difference in mortality observed between artiovenous grafts and artiovenous fistulas in hemodialysis patients started on tunneled catheters.

Medical Nutrition Therapy Slows Time to Dialysis

Medical Nutrition Therapy Slows Time to Dialysis

CKD patients who did not participate in medical nutrition therapy were 3 times more likely to start dialysis than those who did.

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