Diabetes:
Indications for: WELCHOL FOR ORAL SUSPENSION
Adjunct to diet and exercise in type 2 diabetes mellitus.
Limitations of Use:
Not for treatment of type 1 diabetes or diabetic ketoacidosis.
Adult Dosage:
Take with a meal and liquid. 3 tabs twice daily or 6 tabs once daily. Susp: one 3.75g pkt once daily. Empty contents into a glass or cup, add 8oz of water, fruit juice, or diet soft drinks; stir and drink. Do not take susp in its dry form.
Children Dosage:
Not established.
WELCHOL FOR ORAL SUSPENSION Contraindications:
History of bowel obstruction. Serum TG >500mg/dL. History of hypertriglyceridemia-induced pancreatitis.
WELCHOL FOR ORAL SUSPENSION Warnings/Precautions:
TG levels >300mg/dL. Monitor lipids, TG, and non-HDL-C levels prior to initiation and periodically thereafter. Discontinue if acute pancreatitis occurs. Susceptibility to Vit. A, D, E, or K deficiencies. Gastroparesis, other GI motility disorders, history of major GI surgery, or risk for bowel obstruction: not recommended. Dysphagia or swallowing disorders (esp. w/tab form). Phenylketonuria (susp form). Pregnancy.
See Also:
WELCHOL FOR ORAL SUSPENSION Classification:
Bile acid sequestrant.
WELCHOL FOR ORAL SUSPENSION Interactions:
Monitor drugs with a narrow therapeutic index, cyclosporine, glimepiride, glipizide, olmesartan medoxomil, glyburide, levothyroxine, oral contraceptives containing ethinyl estradiol and norethindrone, phenytoin, warfarin, oral vitamin supplements; give at least 4hrs prior to colesevelam. May potentiate metformin extended-release.
Adverse Reactions:
Constipation, dyspepsia, nausea; dysphagia, pancreatitis.
Drug Elimination:
Renal.
Generic Drug Availability:
NO
How Supplied:
Tabs—180; Susp—30 (single-dose pkt)
Hyperlipoproteinemias:
Indications for: WELCHOL FOR ORAL SUSPENSION
Adjunct to diet and exercise: to reduce elevated LDL-C in adults with primary hyperlipidemia (Type IIa); to reduce LDL-C in boys and postmenarchal girls 10–17yrs of age with heterozygous familial hypercholesterolemia after failing an adequate trial of diet therapy and lifestyle modification.
Limitations of Use:
Not studied in Fredrickson Type I, III, IV, V dyslipidemias.
Adults and Children:
<10yrs or premenarchal females: not established. Take with a meal and liquid. 10–17yrs: Susp: one 3.75g pkt once daily. Empty contents into a glass or cup, add 8oz of water, fruit juice, or diet soft drinks; stir and drink. Do not take susp in its dry form. >17yrs: 3 tabs twice daily or 6 tabs once daily. With a statin: may be dosed at the same time or dosed apart.
WELCHOL FOR ORAL SUSPENSION Contraindications:
History of bowel obstruction. Serum TG >500mg/dL. History of hypertriglyceridemia-induced pancreatitis.
WELCHOL FOR ORAL SUSPENSION Warnings/Precautions:
TG levels >300mg/dL. Monitor lipids, TG, and non-HDL-C levels prior to initiation and periodically thereafter. Discontinue if acute pancreatitis occurs. Susceptibility to Vit. A, D, E, or K deficiencies. Gastroparesis, other GI motility disorders, history of major GI surgery, or risk for bowel obstruction: not recommended. Dysphagia or swallowing disorders (esp. w/tab form). Phenylketonuria (susp form). Pregnancy.
See Also:
WELCHOL FOR ORAL SUSPENSION Classification:
Bile acid sequestrant.
WELCHOL FOR ORAL SUSPENSION Interactions:
Monitor drugs with a narrow therapeutic index, cyclosporine, glimepiride, glipizide, olmesartan medoxomil, glyburide, levothyroxine, oral contraceptives containing ethinyl estradiol and norethindrone, phenytoin, warfarin, oral vitamin supplements; give at least 4hrs prior to colesevelam. May potentiate metformin extended-release.
Adverse Reactions:
Constipation, dyspepsia, nausea; dysphagia, pancreatitis.
Drug Elimination:
Renal.
Generic Drug Availability:
NO
How Supplied:
Tabs—180; Susp—30 (single-dose pkt)
