Edema:
Indications for: Triamterene/Hydrochlorothiazide
Edema.
Adult Dosage:
1–2 caps once daily.
Children Dosage:
Not established.
Triamterene/Hydrochlorothiazide Contraindications:
Hyperkalemia. Renal impairment. Anuria. Sulfonamide allergy. Concomitant potassium or K+-sparing diuretics.
Boxed Warning:
Hyperkalemia.
Triamterene/Hydrochlorothiazide Warnings/Precautions:
Risk of hyperkalemia; monitor frequently. Discontinue if serum potassium >5.5mEq/L or <3mEq/L. Diabetes. Acidosis predisposition. Electrolyte imbalance. Hypochloremia with metabolic alkalosis. Excess diuresis. History of renal stones. Gout. Surgery. SLE. Monitor electrolytes, renal function. Hepatic impairment: monitor for hepatic coma, if confusion increases, discontinue for a few days. Severely ill. Elderly. Pregnancy. Nursing mothers: not recommended.
Triamterene/Hydrochlorothiazide Classification:
Diuretic (K+ sparing) + (thiazide).
Triamterene/Hydrochlorothiazide Interactions:
Digoxin, lithium toxicity. Hyperkalemia more likely with ACE inhibitors, parenteral penicillin G. Hypokalemia with ACTH, corticosteroids, amphotericin B. Hyponatremia with sulfonylureas. NSAIDs may cause renal failure. Adjust antidiabetic, antigout medications. May potentiate nondepolarizing muscle relaxants, antihypertensives. Antagonizes oral anticoagulants, methenamine. May interfere with parathyroid tests.
Adverse Reactions:
Drowsiness, muscle cramps, weakness, headache, GI disturbances, dizziness, impotence, arrhythmias, hypotension, dry mouth, urine discoloration; HCTZ: increased risk for non-melanoma skin cancer.
Note:
Formerly known under the brand name Dyazide.
How Supplied:
Contact supplier
Hypertension:
Indications for: Triamterene/Hydrochlorothiazide
Hypertension when normokalemia is essential.
Adult Dosage:
1–2 caps once daily.
Children Dosage:
Not established.
Triamterene/Hydrochlorothiazide Contraindications:
Hyperkalemia. Renal impairment. Anuria. Sulfonamide allergy. Concomitant potassium or K+-sparing diuretics.
Boxed Warning:
Hyperkalemia.
Triamterene/Hydrochlorothiazide Warnings/Precautions:
Risk of hyperkalemia; monitor frequently. Discontinue if serum potassium >5.5mEq/L or <3mEq/L. Diabetes. Acidosis predisposition. Electrolyte imbalance. Hypochloremia with metabolic alkalosis. Excess diuresis. History of renal stones. Gout. Surgery. SLE. Monitor electrolytes, renal function. Hepatic impairment: monitor for hepatic coma, if confusion increases, discontinue for a few days. Severely ill. Elderly. Pregnancy. Nursing mothers: not recommended.
Triamterene/Hydrochlorothiazide Classification:
Diuretic (K+ sparing) + (thiazide).
Triamterene/Hydrochlorothiazide Interactions:
Digoxin, lithium toxicity. Hyperkalemia more likely with ACE inhibitors, parenteral penicillin G. Hypokalemia with ACTH, corticosteroids, amphotericin B. Hyponatremia with sulfonylureas. NSAIDs may cause renal failure. Adjust antidiabetic, antigout medications. May potentiate nondepolarizing muscle relaxants, antihypertensives. Antagonizes oral anticoagulants, methenamine. May interfere with parathyroid tests.
Adverse Reactions:
Drowsiness, muscle cramps, weakness, headache, GI disturbances, dizziness, impotence, arrhythmias, hypotension, dry mouth, urine discoloration; HCTZ: increased risk for non-melanoma skin cancer.
Note:
Formerly known under the brand name Dyazide.
How Supplied:
Contact supplier
