Hereditary angioedema:

Indications for: TAKHZYRO

Prophylaxis to prevent attacks of hereditary angioedema (HAE).

Adult Dosage:

Give by SC inj into abdomen, thigh, or upper arm. Initially 300mg every 2 weeks. May consider 300mg every 4 weeks if well-controlled (eg, attack free) for >6 months.

Children Dosage:

<12yrs: not established.

TAKHZYRO Warnings/Precautions:

Discontinue and treat if severe hypersensitivity reaction occurs. Pregnancy (during 3rd trimester). Nursing mothers.

TAKHZYRO Classification:

Plasma kallikrein inhibitor.

TAKHZYRO Interactions:

May increase activated partial thromboplastin time (aPTT) on assay.

Adverse Reactions:

Inj site reactions, upper respiratory infections, headache, rash, myalgia, dizziness, diarrhea; hypersensitivity, increased AST/ALT.

Generic Drug Availability:


How Supplied:

Single-dose vial—1; single-dose prefilled syringe—1 (w. needle)