Skin infections (topicals):

Indications for: SILVADENE

Prophylaxis and treatment of sepsis in 2nd and 3rd degree burns.

Adult Dosage:

Apply 1–2 times daily aseptically to approximately 1/16 inch depth to cleansed and debrided burns. Reapply promptly if removed. Continue until wound closed.

Children Dosage:

Not established.

SILVADENE Contraindications:

Premature infants. Within first 2 months of birth. Late pregnancy.

SILVADENE Warnings/Precautions:

G6PD deficiency. Impaired renal or hepatic function. Monitor serum sulfa levels and renal function in extensive burns. Avoid eyes. Pregnancy (Cat.B). Nursing mothers: not recommended.

SILVADENE Classification:

Sulfonamide antibacterial.

SILVADENE Interactions:

Leukopenia increased with concomitant cimetidine. May inactivate debriding enzymes.

Adverse Reactions:

Transient leukopenia, skin necrosis, erythema multiforme, skin discoloration, burning sensation, rash, pruritus, interstitial nephritis, reduction in bacterial growth; systemic sulfonamide reactions, fungal overgrowth.

How Supplied:

Crm—20g, 50g, 85g, 400g, 1000g