Indications for: SEYSARA

Non-nodular moderate-to-severe acne vulgaris.

Limitations of Use:

Efficacy beyond 12 weeks and safety beyond 12 months: not established. Not evaluated in treating infections.

Adults and Children:

<9yrs: not recommended. Take with fluids. ≥9yrs (33–54kg): 60mg once daily; (55–84kg): 100mg once daily; (85–136kg): 150mg once daily. Re-evaluate if no improvement after 12 weeks.

SEYSARA Warnings/Precautions:

Discontinue if superinfection develops. History of intracranial hypertension. Monitor for visual disturbances. Overweight women. Evaluate if diarrhea occurs; discontinue if C. difficile-associated diarrhea is suspected or confirmed. Avoid sun or UV light. Pregnancy (during 2nd & 3rd trimester): may cause permanent discoloration of the teeth or reversible inhibition of bone growth. Nursing mothers: not recommended.

SEYSARA Classification:

Tetracycline antibiotic.

SEYSARA Interactions:

Avoid concomitant penicillins, oral retinoids. May need to reduce concomitant anticoagulant dose. Separate dosing from antacids containing aluminum, calcium, magnesium, bismuth subsalicylate, and iron-containing products. Concomitant P-gp substrates (eg, digoxin); monitor for toxicity and reduce dose as needed.

Adverse Reactions:

Nausea; tooth discoloration, enamel hypoplasia, inhibition of bone growth (up to 8yrs of age), C.difficile-associated diarrhea, intracranial hypertension, photosensitivity, CNS effects, male infertility.

Generic Drug Availability:


How Supplied: