Arthritis/rheumatic disorders:

Indications for: Salsalate

Rheumatoid arthritis. Osteoarthritis.

Adult Dosage:

3g daily in divided doses.

Children Dosage:

Not recommended.

Salsalate Contraindications:

Varicella or influenza in teenagers. 3rd trimester pregnancy. Aspirin allergy. Coronary artery bypass graft surgery.

Salsalate Warnings/Precautions:

Advanced renal disease: not recommended. Impaired renal or hepatic function. Hypertension. Heart failure. Edema. Bleeding disorders. Monitor blood, liver, renal function with chronic use. Peptic ulcer. Gastritis. Diabetes. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers: not recommended.

See Also:

    Salsalate Classification:


    Salsalate Interactions:

    PABA may increase serum levels. May potentiate anticoagulants, hypoglycemics, methotrexate. Urinary alkalinizers, antacids, corticosteroids may increase excretion. May antagonize uricosurics and spironolactone.

    Adverse Reactions:

    Salicylism, tinnitus, nausea, dyspepsia, GI bleed, hearing loss, rash (discontinue if occurs). See literature re: risk of cardiovascular events.


    Formerly known under the brand names Disalcid, Salflex.

    How Supplied:

    Contact supplier.