Dry mouth:

Indications for: SALAGEN

Dry mouth (xerostomia) due to radiotherapy for head and neck cancer or Sjogren's syndrome.

Adult Dosage:

Cancer: Initially 5mg three times daily; range 15–30mg daily; max 10mg/dose. Sjogren's syndrome: 5mg four times daily. Moderate hepatic impairment for both: 5mg twice daily.

Children Dosage:

Not recommended.

SALAGEN Contraindications:

Uncontrolled asthma. When miosis is undesirable (iritis, narrow-angle glaucoma).

SALAGEN Warnings/Precautions:

Severe hepatic impairment: not recommended. Cardiovascular disease. Controlled asthma. Chronic bronchitis. COPD. Cholethiasis. Biliary tract disease. Nephrolithiasis. Cognitive or psychiatric disorders. Activities requiring visual acuity. Pregnancy (Cat.C). Nursing mothers: not recommended.

SALAGEN Classification:


SALAGEN Interactions:

Cardiac conduction disturbances with β-blockers. Potentiates parasympathomimetics. Antagonizes anticholinergics (eg, atropine, ipratropium).

Adverse Reactions:

Sweating, nausea, rhinitis, chills, flushing, urinary frequency, dizziness, asthenia, headache, abnormal vision.

How Supplied: