Indications for: PROQUAD

Measles, mumps, rubella, and varicella immunization; may be used if a 2nd dose of measles, mumps, rubella, and varicella vaccine is needed.

Adult Dosage:

Not recommended.

Children Dosage:

<12 months or ≥13yrs: not established. Each dose is 0.5mL. Give by SC or IM inj. First dose at 12–15 months of age (or anytime through 12yrs of age), second dose at 4–6yrs of age.

PROQUAD Contraindications:

Egg, gelatin, or neomycin hypersensitivity. Blood dyscrasias. Leukemia, lymphoma, or other bone marrow or lymphatic malignancy. Primary or acquired immunodeficiency. Family history of congenital or hereditary immunodeficiency. Immunosuppressant therapy. Active untreated tuberculosis. Fever >101.3°F. Pregnancy (Cat.X); avoid pregnancy for 3 months after vaccination.

PROQUAD Warnings/Precautions:

Have epinephrine inj (1:1000) available. History of febrile convulsions or cerebral injury. Thrombocytopenia. Avoid contact with high-risk individuals susceptible to varicella for 6 weeks after vaccination. Post-exposure prophylaxis for measles, mumps, rubella, or varicella. HIV-infected children. Contains albumin; monitor for possible infection transmission (eg, viruses, Creutzfeldt-Jakob disease). Nursing mothers: not recommended.

PROQUAD Classification:


PROQUAD Interactions:

Immunosuppressants (see Contraindications). Avoid salicylates for 6 weeks after vaccination. Defer vaccination for at least 3 months after blood or plasma transfusions or immune globulins. Avoid immune globulin administration for 1 month after vaccination. Separate dosing of measles-containing vaccine by 1 month. If 2nd dose of varicella-containing vaccine needed, separate by 3 months. Concomitant other vaccines: see full labeling. May interfere with tuberculin skin test.

Adverse Reactions:

Inj site reactions, fever, irritability, rash; others.


Report adverse events to VAERS by calling (800) 822-7967.

Generic Drug Availability:


How Supplied:

Single-dose vials—10 (w. diluent)