Hyperacidity, GERD, and ulcers:
Indications for: PRILOSEC OTC
Frequent heartburn (≥2 days/week). Not intended for immediate relief of heartburn (may take 1–4 days for full effect).
Swallow whole. Take before eating in the AM. ≥18yrs: 20mg once daily for 14 days; may repeat 14-day course every 4 months.
<18yrs: not recommended.
PRILOSEC OTC Contraindications:
Trouble or pain swallowing food. Vomiting with blood. Bloody or black stools. Chest or shoulder pain with shortness of breath; sweating; pain spreading to arms, neck, or shoulders; or lightheadedness. Frequent chest pain.
PRILOSEC OTC Warnings/Precautions:
Discontinue if an allergic reaction (eg, rash) occurs. Heartburn >3 months. Frequent wheezing. Unexplained weight loss. Nausea/vomiting. Stomach pain. Discontinue and reevaluate if condition continues or worsens after 14 days, require >1 course of treatment every 4 months; diarrhea or joint pain develops. Pregnancy. Nursing mothers.
PRILOSEC OTC Classification:
Proton pump inhibitor.
PRILOSEC OTC Interactions:
May affect or be affected by blood-thinning agents (eg, warfarin, clopidogrel, cilostazol), antifungals, digoxin, diazepam, tacrolimus, mycophenolate mofetil, antiretrovirals, methotrexate.
Diarrhea, rash, joint pain; severe skin reactions (eg, skin reddening, blisters).
Generic Drug Availability:
Tabs—14, 28, 42