Indications for: Prilocaine HCl

Local anesthesia in dentistry by nerve block or infiltration techniques.

Adult Dosage:

Maxillary infiltration: initially 1–2mL; max recommended dose within a 2-hour period: <70kg: 8mg/kg; ≥70kg: 600mg. Elderly, debilitated, acutely ill: reduce dose.

Children Dosage:

<10yrs: use Clarks rule to calculate dose.

Prilocaine HCl Contraindications:

Congenital or idiopathic methemoglobinemia.

Prilocaine HCl Warnings/Precautions:

Have resuscitative equipment, oxygen, and standard protocol for management of malignant hyperthermia available. G6PD deficiency. Severe shock. Heart block. Hepatic disease. Impaired cardiovascular function. Head and neck block. Monitor cardiovascular and respiratory vital signs. Pregnancy (Cat.B). Nursing mothers.

Prilocaine HCl Classification:

Local anesthetic (amide-type).

Prilocaine HCl Interactions:

Risk of methemoglobinemia with sulfonamides, acetaminophen, acetanilid, aniline dyes, benzocaine, chloroquine, dapsone, naphthalene, nitrates and nitrites, nitrofurantoin, nitroglycerin, nitroprusside, pamaquine, para-aminosalicylic acid, phenacetin, phenobarbital, phenytoin, primaquine, quinine.

Adverse Reactions:

Swelling and persistent paresthesia of lips, oral tissue; CNS effects (eg, excitation, depression, restlessness, anxiety, dizziness, tremors), cardiovascular effects (eg, bradycardia, hypotension, cardiovascular collapse), allergic-type reactions, neurologic effects, increased creatinine phosphokinase.


Formerly known under the brand name Citanest Plain Dental.

How Supplied:

Contact supplier.