Indications for: Oxandrolone

As an adjunct to promote weight gain after extensive surgery, chronic infections, severe trauma, and without definite cause, to offset protein catabolism associated with prolonged corticosteroid administration, and for relief of osteoporotic bone pain.

Adult Dosage:

Individualize. 2.5–20mg daily given in 2–4 divided doses. Treat for 2–4 weeks; may repeat intermittently as needed. Elderly: 5mg twice daily.

Children Dosage:

≤0.1mg/kg/day; may repeat intermittently as needed.

Oxandrolone Contraindications:

Breast (women with hypercalcemia, men) or prostate carcinoma. Nephrosis. Hypercalemia. Pregnancy (Cat.X).

Boxed Warning:

Peliosis hepatis. Liver cell tumors. Blood lipid changes.

Oxandrolone Warnings/Precautions:

Risk of peliosis hepatis, liver cell tumors, blood lipid changes associated with atherosclerosis. Discontinue if cholestatic hepatitis, jaundice, abnormal liver function tests, or hypercalcemia occurs. Cardiovascular disease. COPD. Edematous conditions. Hepatic or renal dysfunction. Monitor hepatic function, serum lipids, Hgb/Hct, and bone age (children) periodically. Monitor for signs of virilization in women; discontinue if mild virilism occurs to prevent irreversible condition. Elderly. Young children. Nursing mothers: not recommended.

Oxandrolone Classification:


Oxandrolone Interactions:

May potentiate warfarin (monitor INR/PT), oral hypoglycemics. Increased risk of edema with ACTH, corticosteroids. May suppress clotting factors II, V, VII and X. May decrease thyroxine-binding globulin and radioactive iodine uptake.

Adverse Reactions:

Peliosis hepatis, premature epiphyseal closure in children, edema, dyslipidemia, hepatic carcinoma, prostatic hypertrophy or carcinoma, gynecomastia, priapism, oligospermia, jaundice, hirsutism, virilization, menstrual irregularities, male pattern baldness, acne, polycythemia, excitation, depression, altered libido, fluid and electrolyte disturbances, decreased glucose tolerance.


Formerly known under the brand name Oxandrin.

How Supplied:

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