Indications for NULECIT:
Iron deficiency anemia in patients on chronic hemodialysis receiving epoetin therapy.
Give by IV infusion (diluted) or slow IV inj (undiluted). 125mg infused over 1 hour or by slow IV inj (at a rate of up to 12.5mg/min). Minimum cumulative dose: 1g given over 8 sequential dialysis sessions; usual max: 125mg/dose.
<6yrs: not recommended. Give by IV infusion (diluted) over 1 hour. ≥6yrs: 1.5mg/kg per dose at 8 sequential dialysis sessions; max: 125mg/dose.
Anemias not caused by iron deficiency. Iron overload.
Hemoglobinopathies. Refractory anemias. Avoid in neonates. Pregnancy (Cat. B). Nursing mothers.
May reduce absorption of concomitant oral iron preparations.
Hypotension, hypertension, GI upset, chest pain, back pain, abdominal pain, pruritus, inj site reaction, cramps, headache, dizziness, syncope, fatigue, fever, dyspnea, tachycardia; rare: hypersensitivity reactions.