Angina:
Indications for: NORVASC
Vasospastic and chronic stable angina.
Adult Dosage:
10mg once daily. Elderly or hepatic impairment: 5mg once daily.
Children Dosage:
Not recommended.
NORVASC Warnings/Precautions:
Severe obstructive coronary disease. Severe aortic stenosis. CHF. Hepatic dysfunction. Pregnancy. Nursing mothers.
NORVASC Classification:
Calcium channel blocker (CCB) (dihydropyridine).
NORVASC Interactions:
May be potentiated by CYP3A inhibitors; monitor and may need to adjust dose. Concomitant CYP3A inducers; monitor BP. Concomitant sildenafil; monitor for hypotension. Concomitant simvastatin: limit simvastatin dose to 20mg/day. May potentiate cyclosporine or tacrolimus; monitor levels and adjust dose.
Adverse Reactions:
Edema, fatigue, palpitations, dizziness, nausea, flushing, abdominal pain, drowsiness.
How Supplied:
Tabs 2.5mg, 10mg—90; 5mg—90, 300
Hypertension:
Indications for: NORVASC
Hypertension.
Adult Dosage:
5mg daily. Adjust at 7–14 day intervals; usual max 10mg daily. Small, fragile, elderly, hepatic impaired, patients on other antihypertensives: 2.5mg daily.
Children Dosage:
<6yrs: not established. 6–17yrs: 2.5–5mg daily.
NORVASC Warnings/Precautions:
Severe obstructive coronary disease. Severe aortic stenosis. CHF. Hepatic dysfunction. Pregnancy. Nursing mothers.
NORVASC Classification:
Calcium channel blocker (CCB) (dihydropyridine).
NORVASC Interactions:
May be potentiated by CYP3A inhibitors; monitor and may need to adjust dose. Concomitant CYP3A inducers; monitor BP. Concomitant sildenafil; monitor for hypotension. Concomitant simvastatin: limit simvastatin dose to 20mg/day. May potentiate cyclosporine or tacrolimus; monitor levels and adjust dose.
Adverse Reactions:
Edema, fatigue, palpitations, dizziness, nausea, flushing, abdominal pain, drowsiness.
How Supplied:
Tabs 2.5mg, 10mg—90; 5mg—90, 300
