Endometriosis:
Indications for: Norethindrone Acetate
Endometriosis.
Adult Dosage:
Initially 5mg daily for 2 weeks, then increase by 2.5mg/day every 2 weeks up to 15mg/day maintenance dose. Continue for 6–9 months unless breakthrough bleeding is intolerable.
Children Dosage:
Not applicable.
Norethindrone Acetate Contraindications:
Thromboembolic disorders. Hepatic dysfunction. Undiagnosed vaginal bleeding. Breast or genital carcinoma. Missed abortion. Pregnancy (Cat.X).
Norethindrone Acetate Warnings/Precautions:
Cardiac or renal dysfunction. Depression. Include Pap smear in pretreatment exam. Conditions aggravated by fluid retention. Discontinue if jaundice, visual disturbances, migraine, or thrombotic disorders occur. Nursing mothers.
Norethindrone Acetate Classification:
Progestin.
Norethindrone Acetate Interactions:
Rifampin may increase metabolism.
Adverse Reactions:
Menstrual and cervical changes, edema, jaundice, rash, depression, mastodynia, decreased glucose tolerance, weight changes, thromboembolic disease, breakthrough bleeding, melasma, chloasma.
Note:
Formerly known under the brand name Aygestin.
How Supplied:
Contact supplier
Menopause and HRT:
Indications for: Norethindrone Acetate
Secondary amenorrhea, abnormal uterine bleeding due to hormonal imbalance without organic pathology.
Adult Dosage:
2.5–10mg daily for 5–10 days during 2nd half of theoretical menstrual cycle after estrogens if needed.
Children Dosage:
Not applicable.
Norethindrone Acetate Contraindications:
Thromboembolic disorders. Hepatic dysfunction. Undiagnosed vaginal bleeding. Breast or genital carcinoma. Missed abortion. Pregnancy (Cat.X).
Norethindrone Acetate Warnings/Precautions:
Cardiac or renal dysfunction. Depression. Include Pap smear in pretreatment exam. Conditions aggravated by fluid retention. Discontinue if jaundice, visual disturbances, migraine, or thrombotic disorders occur. Nursing mothers.
Norethindrone Acetate Classification:
Progestin.
Norethindrone Acetate Interactions:
Rifampin may increase metabolism.
Adverse Reactions:
Menstrual and cervical changes, edema, jaundice, rash, depression, mastodynia, decreased glucose tolerance, weight changes, thromboembolic disease, breakthrough bleeding, melasma, chloasma.
Note:
Formerly known under the brand name Aygestin.
How Supplied:
Contact supplier
