Prostate and other male cancers:

Indications for: NILANDRON

Metastatic prostate cancer (Stage D2), as an adjunct to surgical castration.

Adult Dosage:

300mg once daily for 30 days then 150mg once daily, starting day of or day after surgical castration.

Children Dosage:

Not applicable.

NILANDRON Contraindications:

Severe hepatic impairment or respiratory insufficiency.

Boxed Warning:

Interstitial pneumonitis.

NILANDRON Warnings/Precautions:

Obtain baseline liver and pulmonary function tests, routine chest X-ray. Monitor for interstitial pneumonitis; discontinue if symptoms occur. Monitor liver function for first 4 months then periodically; discontinue if ALT > 2xULN or jaundice occurs. May discolor urine or sclera. Pregnancy (not for use in women). Nursing mothers.

NILANDRON Classification:


NILANDRON Interactions:

Monitor drugs metabolized by CYP450 (eg, Vit. K antagonists, theophylline, phenytoin); may need to adjust dose. May cause alcohol intolerance.

Adverse Reactions:

Hot flushes, impaired night vision, GI upset, increased liver enzymes, constipation, dizziness, abnormal vision, hypertension, hepatitis, interstitial pneumonitis.

How Supplied: