Smoking:

Indications for: NICOTROL INHALER

Adjunct in smoking cessation therapy.

Adult Dosage:

Each cartridge lasts about 20 minutes with frequent continuous puffing and provides nicotine equivalent to about 2 cigarettes. Individualize. Use at least 6 cartridges/day for 1st 3–6 weeks; max 16 cartridges/day for 1st 12 weeks, then reduce gradually over 12 more weeks.

Children Dosage:

Not recommended.

NICOTROL INHALER Contraindications:

Concurrent smoking or other nicotine products.

NICOTROL INHALER Warnings/Precautions:

Sustained use (>6 months): not recommended. Avoid immediately post-MI, in arrhythmias, or severe or worsening angina pectoris. Hypertension. Vasospastic or coronary heart disease. Bronchospastic disease. Severe reactive airway disease: not recommended. Hepatic or moderate/severe renal impairment. Hyperthyroidism. Pheochromocytoma. Diabetes. Esophagitis. Active gastric or peptic ulcers. Elderly. Low doses may be toxic to children and pets. Nasal Spray: nasal mucosal disorders. Pregnancy, labor & delivery: not recommended (attempt nondrug treatment first). Nursing mothers.

See Also:

NICOTROL INHALER Interactions:

Nasal Spray antagonized by nasal vasoconstrictors (eg, xylometazoline). Smoking cessation potentiates theophylline, insulin, β-blockers, pentazocine, oxazepam, tricyclic antidepressants (eg, imipramine), caffeine, acetaminophen, adrenergic antagonists (eg, prazosin, labetalol), others. Smoking cessation antagonizes adrenergic agonists (eg, isoproterenol, phenylephrine), others.

Adverse Reactions:

Local irritation, nausea, diarrhea, hiccup, dyspepsia, headache, dizziness, palpitations, hypertension.

How Supplied:

Inhaler 168 cartridges—1 (w. mouthpieces and case); Nasal Spray 10mL (200 sprays)—4 (w. metered spray pump)