Indications for: Naltrexone
Adjunct in treatment of alcohol or narcotic dependence.
Confirm 7–10 day opioid-free period, if questionable do Narcan challenge test (see full labeling). ≥18yrs: Alcoholism: 50mg daily. Narcotic dependence: Initially 25mg, if no withdrawal symptoms increase to 50mg daily; alternative dosing schedules: see full labeling.
<18yrs: not recommended.
Concomitant opioids, current opioid dependence, or acute opioid withdrawal. Failed Narcan challenge test or (+) urine screen for opioids. Acute hepatitis. Liver failure.
Liver disease. Monitor liver function. Warn patients of danger of attempting to overcome opiate blockade. Severe renal dysfunction. Possible acute abstinence syndrome. Depression. Suicidal ideation. Pregnancy (Cat.C). Nursing mothers.
Thioridazine increases sedation. Antagonizes opioids (eg, antitussives, antidiarrheals, analgesics). Disulfiram.
Hepatotoxicity, withdrawal reactions; others, see full labeling.
Formerly known under the brand name Revia.