Bleeding disorders:

Indications for MULPLETA:

Thrombocytopenia in adults with chronic liver disease who are scheduled to undergo a procedure.


Start treatment 8–14 days prior to a procedure. Should undergo procedure within 2–8 days after last dose. Take with or without food. 3mg once daily for 7 days.


Not established.


Obtain platelet count prior to treatment and not more than 2 days prior to procedure. Increased thrombotic risk with known risk factors (eg, Factor V Leiden, Prothrombin 20210A, Antithrombin deficiency, Protein C or S deficiency). Ongoing or prior thrombosis or absence of hepatopetal blood flow: use only if potential benefit justifies risk. Do not use to normalize platelet counts. Pregnancy: may cause fetal harm. Nursing mothers: not recommended (during and for ≥28 days after last dose).

Pharmacologic Class:

Thrombopoietin receptor agonist.

Adverse Reactions:

Headache; portal vein thrombosis.

Generic Availability:


How Supplied:


Pricing for MULPLETA

7 tablets of 3mg dose pack (Qty: 1)
Appx. price $8680