Thyroid disease:
Indications for: Methimazole
Hyperthyroidism.
Adult Dosage:
Initially 15–60mg daily in 3 divided doses, depending on severity of disease. Maintenance: 5–15mg daily.
Children Dosage:
Initially 0.4mg/kg daily in 3 divided doses. Maintenance: ½ initial dose.
Methimazole Contraindications:
Nursing mothers.
Methimazole Warnings/Precautions:
Discontinue if agranulocytosis, aplastic anemia, exfoliate dermatitis, hepatitis, or elevated liver transaminases (3xULN) occurs. Monitor prothrombin time, WBC, bone marrow function. Pregnancy (Cat.D).
Methimazole Classification:
Antithyroid.
Methimazole Interactions:
Potentiates anticoagulants.
Adverse Reactions:
Rash, GI disturbances, arthralgia, paresthesia, hair and taste loss, agranulocytosis, blood dyscrasias, aplastic anemia, hepatic dysfunction, drug fever, lupus-like syndrome, insulin autoimmune syndrome, periarteritis; nephritis (rare).
Note:
Formerly known under the brand name Tapazole.
How Supplied:
Contact supplier
