Angina:
Indications for: INDERAL LA
Long-term management of angina. Hypertrophic subaortic stenosis.
Adult Dosage:
Angina: Initially 80mg once daily. May increase at 3–7 day intervals; max 320mg daily. Stenosis: 80–160mg once daily.
Children Dosage:
Not recommended.
INDERAL LA Contraindications:
Asthma. Sinus bradycardia. 2nd- or 3rd-degree AV block. Overt heart failure. Cardiogenic shock.
INDERAL LA Warnings/Precautions:
CHF. Wolff-Parkinson-White syndrome. Renal or hepatic dysfunction. Bronchospastic disease, COPD. Diabetes. Hyperthyroidism. Surgery. SLE. Avoid abrupt cessation. Elderly. Pregnancy (Cat.C). Nursing mothers.
See Also:
INDERAL LA Classification:
Beta-blocker.
INDERAL LA Interactions:
Potentiated by alcohol, CNS depressants, other antihypertensives, antithyroid drugs, haloperidol, chlorpromazine, cimetidine. Bradycardia with catecholamine-depleting drugs. Antagonized by NSAIDs, barbiturates, rifampin, phenytoin. May increase cardiac effects of calcium channel blockers, digitalis, lidocaine. Potentiates theophylline, antipyrine, lidocaine. May block epinephrine. May interfere with glaucoma screening tests.
Adverse Reactions:
Heart failure, hypotension, bronchospasm, bradycardia, heart block, fatigue, dizziness, depression, GI upset, skin reactions (eg, rash, Stevens-Johnson syndrome, urticaria), pharyngitis, agranulocytosis.
Drug Elimination:
Renal. Half-life: 10hrs.
How Supplied:
Tabs—contact supplier; LA—100
Hypertension:
Indications for: INDERAL LA
Hypertension. Adjunct in pheochromocytoma.
Adult Dosage:
Initially 80mg daily. Usual maintenance: 120–160mg daily; max 640mg daily.
Children Dosage:
Not recommended.
INDERAL LA Contraindications:
Asthma. Sinus bradycardia. 2nd- or 3rd-degree AV block. Overt heart failure. Cardiogenic shock.
INDERAL LA Warnings/Precautions:
CHF. Wolff-Parkinson-White syndrome. Renal or hepatic dysfunction. Bronchospastic disease, COPD. Diabetes. Hyperthyroidism. Surgery. SLE. Avoid abrupt cessation. Elderly. Pregnancy (Cat.C). Nursing mothers.
See Also:
INDERAL LA Classification:
Beta-blocker.
INDERAL LA Interactions:
Potentiated by alcohol, CNS depressants, other antihypertensives, antithyroid drugs, haloperidol, chlorpromazine, cimetidine. Bradycardia with catecholamine-depleting drugs. Antagonized by NSAIDs, barbiturates, rifampin, phenytoin. May increase cardiac effects of calcium channel blockers, digitalis, lidocaine. Potentiates theophylline, antipyrine, lidocaine. May block epinephrine. May interfere with glaucoma screening tests.
Adverse Reactions:
Heart failure, hypotension, bronchospasm, bradycardia, heart block, fatigue, dizziness, depression, GI upset, skin reactions (eg, rash, Stevens-Johnson syndrome, urticaria), pharyngitis, agranulocytosis.
Note:
Formerly known under the brand name Inderal.
Drug Elimination:
Renal. Half-life: 3–6hrs.
How Supplied:
Tabs—contact supplier; LA—100
Migraine and headache:
Indications for: INDERAL LA
Migraine prophylaxis.
Adult Dosage:
Initially 80mg daily. Usual range: 160–240mg daily. Discontinue if poor result after 4–6 weeks.
Children Dosage:
Not recommended.
INDERAL LA Contraindications:
Asthma. Sinus bradycardia. 2nd- or 3rd-degree AV block. Overt heart failure. Cardiogenic shock.
INDERAL LA Warnings/Precautions:
CHF. Wolff-Parkinson-White syndrome. Renal or hepatic dysfunction. Bronchospastic disease, COPD. Diabetes. Hyperthyroidism. Surgery. SLE. Avoid abrupt cessation. Elderly. Pregnancy (Cat.C). Nursing mothers.
See Also:
INDERAL LA Classification:
Beta-blocker.
INDERAL LA Interactions:
Potentiated by alcohol, CNS depressants, other antihypertensives, antithyroid drugs, haloperidol, chlorpromazine, cimetidine. Bradycardia with catecholamine-depleting drugs. Antagonized by NSAIDs, barbiturates, rifampin, phenytoin. May increase cardiac effects of calcium channel blockers, digitalis, lidocaine. Potentiates theophylline, antipyrine, lidocaine. May block epinephrine. May interfere with glaucoma screening tests.
Adverse Reactions:
Heart failure, hypotension, bronchospasm, bradycardia, heart block, fatigue, dizziness, depression, GI upset, skin reactions (eg, rash, Stevens-Johnson syndrome, urticaria), pharyngitis, agranulocytosis.
Note:
Formerly known under the brand name Inderal.
Drug Elimination:
Renal. Half-life: 3–6hrs.
How Supplied:
Tabs—contact supplier; LA—100
