Select therapeutic use:

Arthritis/rheumatic disorders:

Indications for: Ibuprofen

Rheumatoid arthritis (RA). Osteoarthritis (OA). Juvenile arthritis (JRA).

Adult Dosage:

RA, OA: 400–800mg 3–4 times daily; max 3.2g/day.

Children Dosage:

JRA: 30–40mg/kg per day in 3–4 doses. May use 20mg/kg per day in 3–4 doses for milder disease.

Ibuprofen Contraindications:

Aspirin allergy. 3rd trimester pregnancy. Coronary artery bypass graft surgery.

Ibuprofen Warnings/Precautions:

Advanced renal disease: not recommended. History of upper GI disease. Active peptic ulcer. Impaired renal or hepatic function. Edema. Hypertension. Cardiac failure. Bleeding disorders. Diabetes. Monitor blood, hepatic, renal, and ocular function in chronic use. Discontinue if visual or liver dysfunction occurs. Dehydration. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers: not recommended.

Ibuprofen Classification:

NSAID (propionic acid deriv.).

Ibuprofen Interactions:

Avoid aspirin. May increase bleeding with anticoagulants. Increases serum lithium levels. May increase toxicity of methotrexate. May decrease effect of furosemide, thiazide diuretics. Increased risk of GI bleed with alcohol.

Adverse Reactions:

Peptic ulcer or perforation, GI bleeding, vision disorders, nausea, epigastric pain, heartburn, dizziness, rash (discontinue if occurs), edema, renal papillary necrosis, jaundice, hepatitis. See literature re: risk of cardiovascular events.

How Supplied:

Contact supplier.

Dysmenorrhea:

Indications for: Ibuprofen

Dysmenorrhea.

Adult Dosage:

400mg every 4 hours; max 3.2g/day. May take with food or milk.

Children Dosage:

Not applicable.

Ibuprofen Contraindications:

Aspirin allergy. 3rd trimester pregnancy. Coronary artery bypass graft surgery.

Ibuprofen Warnings/Precautions:

Advanced renal disease: not recommended. History of upper GI disease. Active peptic ulcer. Impaired renal or hepatic function. Edema. Hypertension. Cardiac failure. Bleeding disorders. Diabetes. Monitor blood, hepatic, renal, and ocular function in chronic use. Discontinue if visual or liver dysfunction occurs. Dehydration. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers: not recommended.

Ibuprofen Classification:

NSAID (propionic acid deriv.).

Ibuprofen Interactions:

Avoid aspirin. May increase bleeding with anticoagulants. Increases serum lithium levels. May increase toxicity of methotrexate. May decrease effect of furosemide, thiazide diuretics. Increased risk of GI bleed with alcohol.

Adverse Reactions:

Peptic ulcer or perforation, GI bleeding, vision disorders, nausea, epigastric pain, heartburn, dizziness, rash (discontinue if occurs), edema, renal papillary necrosis, jaundice, hepatitis. See literature re: risk of cardiovascular events.

How Supplied:

Contact supplier.

Nonnarcotic analgesics:

Indications for: Ibuprofen

Mild to moderate pain. Fever.

Adult Dosage:

Pain: 400mg every 4–6 hrs as needed.

Children Dosage:

Use caplets, chewables, suspension, or drops. <6 months: not recommended. ≥6 months: Fever <102.5°F: 5mg/kg every 6–8 hours. Fever >102.5°F or pain: 10mg/kg every 6–8 hours; max 40mg/kg/day.

Ibuprofen Contraindications:

Aspirin allergy. 3rd trimester pregnancy. Coronary artery bypass graft surgery.

Ibuprofen Warnings/Precautions:

Advanced renal disease: not recommended. History of upper GI disease. Active peptic ulcer. Impaired renal or hepatic function. Edema. Hypertension. Cardiac failure. Bleeding disorders. Diabetes. Monitor blood, hepatic, renal, and ocular function in chronic use. Discontinue if visual or liver dysfunction occurs. Dehydration. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers: not recommended.

Ibuprofen Classification:

NSAID (propionic acid deriv.).

Ibuprofen Interactions:

Avoid aspirin. May increase bleeding with anticoagulants, toxicity of methotrexate. Increases serum lithium levels. May decrease effect of furosemide, thiazide diuretics.

Adverse Reactions:

Peptic ulcer or perforation, GI bleeding, vision disorders, nausea, epigastric pain, heartburn, dizziness, rash (discontinue if occurs), edema, renal papillary necrosis, jaundice, hepatitis. See literature re: risk of cardiovascular events.

How Supplied:

Contact supplier.