Edema:
Indications for: Hydrochlorothiazide
Edema.
Adult Dosage:
25–100mg daily in single or divided doses; may give on intermittent schedule (every other day or 3–5 days/wk).
Children Dosage:
<6mos: up to 3mg/kg/day in 2 divided doses. ≥6mos: 1–2mg/kg/day in 1–2 divided doses. Max (<2yrs): 37.5mg/day; (2–12yrs): 100mg/day.
Hydrochlorothiazide Contraindications:
Anuria. Sulfonamide allergy.
Hydrochlorothiazide Warnings/Precautions:
Renal or hepatic impairment. Arrhythmia. Diabetes. Gout. Asthma. SLE. Postsympathectomy. Excessive fluid loss. Monitor electrolytes, BUN (if high). K+ supplements or K+ sparing diuretics may be needed. Discontinue if electrolyte disorders develop rapidly. Pregnancy (Cat.B). Nursing mothers: not recommended.
Hydrochlorothiazide Classification:
Diuretic (thiazide).
Hydrochlorothiazide Interactions:
Digitalis, lithium toxicity. Adjust antidiabetic, antigout medications. NSAIDs may cause renal failure. ACTH, corticosteroids, amphotericin B increase hypokalemia risk. Orthostatic hypotension with alcohol, CNS depressants. Hyperglycemia, hyperuricemia more likely with diazoxide. Antagonized by NSAIDs. May potentiate nondepolarizing muscle relaxants. May antagonize norepinephrine. May interfere with parathyroid tests.
Adverse Reactions:
Electrolyte disorders (esp. hypokalemia), hyperglycemia, hyperuricemia, photosensitivity, orthostatic hypotension, GI disturbances, adverse lipid values.
Note:
Formerly known under the brand names Esidrix, Hydro-D, Hydrodiuril, Microzide.
How Supplied:
Contact supplier
Hypertension:
Indications for: Hydrochlorothiazide
Hypertension.
Adult Dosage:
Initially 25mg once daily; usual max 50mg/day in 1–2 divided doses.
Children Dosage:
<6mos: up to 3mg/kg/day in 2 divided doses. ≥6mos: 1–2mg/kg/day in 1–2 divided doses. Max (<2yrs): 37.5mg/day; (2–12yrs): 100mg/day.
Hydrochlorothiazide Contraindications:
Anuria. Sulfonamide allergy.
Hydrochlorothiazide Warnings/Precautions:
Renal or hepatic impairment. Arrhythmia. Diabetes. Gout. Asthma. SLE. Postsympathectomy. Excessive fluid loss. Monitor electrolytes, BUN (if high). K+ supplements or K+ sparing diuretics may be needed. Discontinue if electrolyte disorders develop rapidly. Pregnancy (Cat.B). Nursing mothers: not recommended.
Hydrochlorothiazide Classification:
Diuretic (thiazide).
Hydrochlorothiazide Interactions:
Digitalis, lithium toxicity. Adjust antidiabetic, antigout medications. NSAIDs may cause renal failure. ACTH, corticosteroids, amphotericin B increase hypokalemia risk. Orthostatic hypotension with alcohol, CNS depressants. Hyperglycemia, hyperuricemia more likely with diazoxide. Antagonized by NSAIDs. May potentiate nondepolarizing muscle relaxants. May antagonize norepinephrine. May interfere with parathyroid tests.
Adverse Reactions:
Electrolyte disorders (esp. hypokalemia), hyperglycemia, hyperuricemia, photosensitivity, orthostatic hypotension, GI disturbances, adverse lipid values.
Note:
Formerly known under the brand names Esidrix, Hydro-D, Hydrodiuril, Microzide.
How Supplied:
Contact supplier
