Arthritis/rheumatic disorders:

Indications for: GELSYN-3

Treatment of pain in osteoarthritis of the knee in patients who have failed nonpharmacologic therapy and simple analgesics (eg, acetaminophen).

Adult Dosage:

Remove synovial fluid or effusion before inj. Give as a single intra-articular inj. >21yrs: 2mL in one knee only at weekly intervals for 3 weeks.

Children Dosage:

≤21yrs: not established.

GELSYN-3 Contraindications:

Knee joint infections. Skin diseases or infections in area of the inj site.

GELSYN-3 Warnings/Precautions:

Do not inject by intravascular route. Severe intra-articular effusion. Lymphatic or venous stasis in leg. Advise patients to avoid strenuous or prolonged weight-bearing activities for approx. 48hrs following inj. Pregnancy, nursing mothers: not established.

GELSYN-3 Classification:


GELSYN-3 Interactions:

Avoid use of disinfectants containing quaternary ammonium salts; hyaluronan can precipitate in their presence. Concomitant other intra-articular inj: not studied.

Adverse Reactions:

Inj site pain, arthralgia, joint effusion/warmth/stiffness/swelling, arthritis, gait disturbance, arthropathy.

Generic Drug Availability:


How Supplied:

Single-use pre-filled syringe—1 (w. needle)