Select therapeutic use:

Bone disorders:

Indications for: EVISTA

Prevention and treatment of osteoporosis in postmenopausal women.

Adult Dosage:

60mg once daily.

Children Dosage:

Not recommended.

EVISTA Contraindications:

Active or history of venous thromboembolic events. Nursing mothers. Pregnancy (Cat.X). Women who may become pregnant.

EVISTA Warnings/Precautions:

Not for use in premenopausal women. Concomitant systemic estrogen therapy: not recommended. Discontinue 72 hours before, and during prolonged immobilization; resume when fully ambulatory. Coronary heart disease or risk of coronary event (increased risk of death due to stroke). Hepatic dysfunction. Moderate to severe renal impairment.

EVISTA Classification:

Selective estrogen receptor modulator (SERM).

EVISTA Interactions:

May antagonize warfarin; monitor. Avoid concomitant cholestyramine, other anion exchange resins. Caution with other highly protein-bound drugs (eg, diazepam, diazoxide, lidocaine).

Adverse Reactions:

Hot flashes, leg cramps, peripheral edema, flu syndrome, arthralgia, sweating; rare: venous thromboembolic events.

How Supplied:

Tabs—30, 100, 2000

Breast cancer:

Indications for: EVISTA

Reduction in risk of invasive breast cancer in postmenopausal women: with osteoporosis and/or at high risk for invasive breast cancer.

Adult Dosage:

60mg once daily.

Children Dosage:

Not recommended.

EVISTA Contraindications:

Active or history of venous thromboembolic events. Nursing mothers. Pregnancy (Cat.X). Women who may become pregnant.

EVISTA Warnings/Precautions:

Not for use in premenopausal women. Concomitant systemic estrogen therapy: not recommended. Discontinue 72 hours before, and during prolonged immobilization; resume when fully ambulatory. Coronary heart disease or risk of coronary event (increased risk of death due to stroke). Hepatic dysfunction. Moderate to severe renal impairment.

EVISTA Classification:

Selective estrogen receptor modulator (SERM).

EVISTA Interactions:

May antagonize warfarin; monitor. Avoid concomitant cholestyramine, other anion exchange resins. Caution with other highly protein-bound drugs (eg, diazepam, diazoxide, lidocaine).

Adverse Reactions:

Hot flashes, leg cramps, peripheral edema, flu syndrome, arthralgia, sweating; rare: venous thromboembolic events.

How Supplied:

Tabs—30, 100, 2000