Sleep-wake disorders:
Indications for: Estazolam
Short-term treatment of insomnia.
Adult Dosage:
Initially 1mg at bedtime. May increase to 2mg nightly. Small or debilitated elderly: initially 0.5mg.
Children Dosage:
<18yrs: not recommended.
Estazolam Contraindications:
Concomitant ketoconazole, itraconazole. Pregnancy (Cat.X).
Estazolam Warnings/Precautions:
Drug or alcohol abuse. Suicidal tendencies. Depression. Renal, hepatic, or respiratory impairment. Avoid abrupt cessation after prolonged use. Elderly. Debilitated. Nursing mothers: not recommended.
Estazolam Classification:
Benzodiazepine.
Estazolam Interactions:
Potentiates CNS depression with alcohol, other CNS depressants. Caution with CYP3A inhibitors (eg, nefazodone, fluvoxamine, cimetidine, diltiazem, isoniazid, other macrolides): consider dose reduction.
Adverse Reactions:
CNS depression, complex sleep-related behaviors (eg, sleep-driving), hypokinesia, dizziness, incoordination, confusion, constipation, anxiety, paradoxical excitement; anaphylaxis, angioedema.
Note:
Formerly known under the brand name Prosom.
How Supplied:
Contact supplier.
