Colorectal disorders:
Indications for: ENTOCORT EC
Mild to moderate active Crohn's disease of the ileum and/or ascending colon in patients ≥8yrs of age and maintenance of clinical remission for up to 3 months in adults.
Adult Dosage:
Swallow whole. Treatment: 9mg once daily in the AM for up to 8 wks; may repeat an 8-week course. Maintenance of remission: 6mg once daily for up to 3 months. Taper other systemic steroids when transferring to budesonide. Hepatic impairment (moderate): consider 3mg once daily; (severe): avoid.
Children Dosage:
<8yrs: not established. Treatment: 8–17yrs (>25kg): 9mg once daily in the AM for up to 8 wks, then 6mg once daily for 2 wks.
ENTOCORT EC Warnings/Precautions:
Systemic fungal, viral, or mycobacterial infections. Hypertension. Diabetes. Osteoporosis. Peptic ulcer. Glaucoma. Cataracts. If exposed to chickenpox or measles, consider prophylactic passive immune therapy. Supplement with systemic steroid in surgery and stress. Caution when transferring from steroids with high systemic availability. Moderate hepatic impairment: monitor for hypercorticism and consider reducing the dose. Elderly. Pregnancy. Nursing mothers.
ENTOCORT EC Classification:
Steroid.
ENTOCORT EC Interactions:
Avoid grapefruit juice. Systemic effects potentiated by CYP3A4 inhibitors (eg, ketoconazole, itraconazole, ritonavir, indinavir, saquinavir, erythromycin, cyclosporine); avoid.
Adverse Reactions:
Headache, respiratory infection, nausea, back pain, dyspepsia, dizziness, abdominal pain, flatulence, vomiting, fatigue, pain; hypercorticism.
How Supplied:
Caps—100
